Kopetzki E - Search Results

1

Converting blood coagulation factor IXa into factor Xa: dramatic increase in amidolytic activity identifies important active site determinants.

Hopfner KP, Brandstetter H, Karcher A, Kopetzki E, Huber R, Engh RA, Bode W. Hopfner KP, et al. Among authors: kopetzki e. EMBO J. 1997 Nov 17;16(22):6626-35. doi: 10.1093/emboj/16.22.6626. EMBO J. 1997. PMID: 9362477 Free PMC article.

2

Crystal structures of uninhibited factor VIIa link its cofactor and substrate-assisted activation to specific interactions.

Sichler K, Banner DW, D'Arcy A, Hopfner KP, Huber R, Bode W, Kresse GB, Kopetzki E, Brandstetter H. Sichler K, et al. Among authors: kopetzki e. J Mol Biol. 2002 Sep 20;322(3):591-603. doi: 10.1016/s0022-2836(02)00747-7. J Mol Biol. 2002. PMID: 12225752

3

The influence of residue 190 in the S1 site of trypsin-like serine proteases on substrate selectivity is universally conserved.

Sichler K, Hopfner KP, Kopetzki E, Huber R, Bode W, Brandstetter H. Sichler K, et al. Among authors: kopetzki e. FEBS Lett. 2002 Oct 23;530(1-3):220-4. doi: 10.1016/s0014-5793(02)03495-6. FEBS Lett. 2002. PMID: 12387896 Free article.

4

Physiological fIXa activation involves a cooperative conformational rearrangement of the 99-loop.

Sichler K, Kopetzki E, Huber R, Bode W, Hopfner KP, Brandstetter H. Sichler K, et al. Among authors: kopetzki e. J Biol Chem. 2003 Feb 7;278(6):4121-6. doi: 10.1074/jbc.M210722200. Epub 2002 Nov 19. J Biol Chem. 2003. PMID: 12444082 Free article.

5

New enzyme lineages by subdomain shuffling.

Hopfner KP, Kopetzki E, Kresse GB, Bode W, Huber R, Engh RA. Hopfner KP, et al. Among authors: kopetzki e. Proc Natl Acad Sci U S A. 1998 Aug 18;95(17):9813-8. doi: 10.1073/pnas.95.17.9813. Proc Natl Acad Sci U S A. 1998. PMID: 9707558 Free PMC article.

6

Coagulation factor IXa: the relaxed conformation of Tyr99 blocks substrate binding.

Hopfner KP, Lang A, Karcher A, Sichler K, Kopetzki E, Brandstetter H, Huber R, Bode W, Engh RA. Hopfner KP, et al. Among authors: kopetzki e. Structure. 1999 Aug 15;7(8):989-96. doi: 10.1016/s0969-2126(99)80125-7. Structure. 1999. PMID: 10467148 Free article.

7

Dramatic enhancement of the catalytic activity of coagulation factor IXa by alcohols.

Sturzebecher J, Kopetzki E, Bode W, Hopfner KP. Sturzebecher J, et al. Among authors: kopetzki e. FEBS Lett. 1997 Jul 28;412(2):295-300. doi: 10.1016/s0014-5793(97)00811-9. FEBS Lett. 1997. PMID: 9256238 Free article.

8

Structural basis of the adaptive molecular recognition by MMP9.

Cha H, Kopetzki E, Huber R, Lanzendörfer M, Brandstetter H. Cha H, et al. Among authors: kopetzki e. J Mol Biol. 2002 Jul 26;320(5):1065-79. doi: 10.1016/s0022-2836(02)00558-2. J Mol Biol. 2002. PMID: 12126625

9

CD4-anchoring HIV-1 fusion inhibitor with enhanced potency and in vivo stability.

Ji C, Kopetzki E, Jekle A, Stubenrauch KG, Liu X, Zhang J, Rao E, Schlothauer T, Fischer S, Cammack N, Heilek G, Ries S, Sankuratri S. Ji C, et al. Among authors: kopetzki e. J Biol Chem. 2009 Feb 20;284(8):5175-85. doi: 10.1074/jbc.M808745200. Epub 2008 Dec 19. J Biol Chem. 2009. PMID: 19097993 Free article.

10

Glycoprotein biosynthesis in Saccharomyces cerevisiae: ngd29, an N-glycosylation mutant allelic to och1 having a defect in the initiation of outer chain formation.

Lehle L, Eiden A, Lehnert K, Haselbeck A, Kopetzki E. Lehle L, et al. Among authors: kopetzki e. FEBS Lett. 1995 Aug 14;370(1-2):41-5. doi: 10.1016/0014-5793(95)00789-c. FEBS Lett. 1995. PMID: 7649302 Free article.

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