Jacobs J - Search Results

1

MPc2, a new murine homolog of the Drosophila polycomb protein is a member of the mouse polycomb transcriptional repressor complex.

Alkema MJ, Jacobs J, Voncken JW, Jenkins NA, Copeland NG, Satijn DP, Otte AP, Berns A, van Lohuizen M. Alkema MJ, et al. Among authors: jacobs j. J Mol Biol. 1997 Nov 14;273(5):993-1003. doi: 10.1006/jmbi.1997.1372. J Mol Biol. 1997. PMID: 9367786

2

The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus.

Jacobs JJ, Kieboom K, Marino S, DePinho RA, van Lohuizen M. Jacobs JJ, et al. Nature. 1999 Jan 14;397(6715):164-8. doi: 10.1038/16476. Nature. 1999. PMID: 9923679

3

Cellular memory of transcriptional states by Polycomb-group proteins.

Jacobs JJ, van Lohuizen M. Jacobs JJ, et al. Semin Cell Dev Biol. 1999 Apr;10(2):227-35. doi: 10.1006/scdb.1999.0304. Semin Cell Dev Biol. 1999. PMID: 10441076 Review.

4

Bmi-1 collaborates with c-Myc in tumorigenesis by inhibiting c-Myc-induced apoptosis via INK4a/ARF.

Jacobs JJ, Scheijen B, Voncken JW, Kieboom K, Berns A, van Lohuizen M. Jacobs JJ, et al. Genes Dev. 1999 Oct 15;13(20):2678-90. doi: 10.1101/gad.13.20.2678. Genes Dev. 1999. PMID: 10541554 Free PMC article.

5

Senescence bypass screen identifies TBX2, which represses Cdkn2a (p19(ARF)) and is amplified in a subset of human breast cancers.

Jacobs JJ, Keblusek P, Robanus-Maandag E, Kristel P, Lingbeek M, Nederlof PM, van Welsem T, van de Vijver MJ, Koh EY, Daley GQ, van Lohuizen M. Jacobs JJ, et al. Nat Genet. 2000 Nov;26(3):291-9. doi: 10.1038/81583. Nat Genet. 2000. PMID: 11062467

6

The T-box repressors TBX2 and TBX3 specifically regulate the tumor suppressor gene p14ARF via a variant T-site in the initiator.

Lingbeek ME, Jacobs JJ, van Lohuizen M. Lingbeek ME, et al. Among authors: jacobs jj. J Biol Chem. 2002 Jul 19;277(29):26120-7. doi: 10.1074/jbc.M200403200. Epub 2002 May 8. J Biol Chem. 2002. PMID: 12000749 Free article.

7

Polycomb repression: from cellular memory to cellular proliferation and cancer.

Jacobs JJ, van Lohuizen M. Jacobs JJ, et al. Biochim Biophys Acta. 2002 Jun 21;1602(2):151-61. doi: 10.1016/s0304-419x(02)00052-5. Biochim Biophys Acta. 2002. PMID: 12020801 Review.

8

The Bmi-1 oncogene induces telomerase activity and immortalizes human mammary epithelial cells.

Dimri GP, Martinez JL, Jacobs JJ, Keblusek P, Itahana K, Van Lohuizen M, Campisi J, Wazer DE, Band V. Dimri GP, et al. Among authors: jacobs jj. Cancer Res. 2002 Aug 15;62(16):4736-45. Cancer Res. 2002. PMID: 12183433

9

Control of the replicative life span of human fibroblasts by p16 and the polycomb protein Bmi-1.

Itahana K, Zou Y, Itahana Y, Martinez JL, Beausejour C, Jacobs JJ, Van Lohuizen M, Band V, Campisi J, Dimri GP. Itahana K, et al. Among authors: jacobs jj. Mol Cell Biol. 2003 Jan;23(1):389-401. doi: 10.1128/MCB.23.1.389-401.2003. Mol Cell Biol. 2003. PMID: 12482990 Free PMC article.

10

Ink4a and Arf differentially affect cell proliferation and neural stem cell self-renewal in Bmi1-deficient mice.

Bruggeman SW, Valk-Lingbeek ME, van der Stoop PP, Jacobs JJ, Kieboom K, Tanger E, Hulsman D, Leung C, Arsenijevic Y, Marino S, van Lohuizen M. Bruggeman SW, et al. Among authors: jacobs jj. Genes Dev. 2005 Jun 15;19(12):1438-43. doi: 10.1101/gad.1299305. Genes Dev. 2005. PMID: 15964995 Free PMC article.

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