Kadwell SH - Search Results

1

Human recombinant phosphodiesterase 4B2B binds (R)-rolipram at a single site with two affinities.

Rocque WJ, Tian G, Wiseman JS, Holmes WD, Zajac-Thompson I, Willard DH, Patel IR, Wisely GB, Clay WC, Kadwell SH, Hoffman CR, Luther MA. Rocque WJ, et al. Among authors: kadwell sh. Biochemistry. 1997 Nov 18;36(46):14250-61. doi: 10.1021/bi971112e. Biochemistry. 1997. PMID: 9369498

2

17 beta-(N-tert-butylcarbamoyl)-4-aza-5 alpha-androstan-1-en-3-one is an active site-directed slow time-dependent inhibitor of human steroid 5 alpha-reductase 1.

Tian G, Stuart JD, Moss ML, Domanico PL, Bramson HN, Patel IR, Kadwell SH, Overton LK, Kost TA, Mook RA Jr, et al. Tian G, et al. Among authors: kadwell sh. Biochemistry. 1994 Mar 1;33(8):2291-6. doi: 10.1021/bi00174a041. Biochemistry. 1994. PMID: 8117686

3

Inhibition of human steroid 5alpha reductases type I and II by 6-aza-steroids: structural determinants of one-step vs two-step mechanism.

Moss ML, Kuzmic P, Stuart JD, Tian G, Peranteau AG, Frye SV, Kadwell SH, Kost TA, Overton LK, Patel IR. Moss ML, et al. Among authors: kadwell sh. Biochemistry. 1996 Mar 19;35(11):3457-64. doi: 10.1021/bi952472+. Biochemistry. 1996. PMID: 8639496

4

Expression, purification, and characterization of the human receptor activator of NF-kappaB ligand (RANKL) extracellular domain.

Willard D, Chen WJ, Barrett G, Blackburn K, Bynum J, Consler T, Hoffman C, Horne E, Iannone MA, Kadwell S, Parham J, Ellis B. Willard D, et al. Protein Expr Purif. 2000 Oct;20(1):48-57. doi: 10.1006/prep.2000.1278. Protein Expr Purif. 2000. PMID: 11035950

5

Structure of the Tie2 RTK domain: self-inhibition by the nucleotide binding loop, activation loop, and C-terminal tail.

Shewchuk LM, Hassell AM, Ellis B, Holmes WD, Davis R, Horne EL, Kadwell SH, McKee DD, Moore JT. Shewchuk LM, et al. Among authors: kadwell sh. Structure. 2000 Nov 15;8(11):1105-13. doi: 10.1016/s0969-2126(00)00516-5. Structure. 2000. PMID: 11080633 Free article.

6

Production and characterization of an estrogen receptor beta subtype-specific mouse monoclonal antibody.

Su JL, McKee DD, Ellis B, Kadwell SH, Wisely GB, Moore LB, Triantafillou JA, Kost TA, Fuqua S, Moore JT. Su JL, et al. Among authors: kadwell sh. Hybridoma. 2000 Dec;19(6):481-7. doi: 10.1089/027245700750053977. Hybridoma. 2000. PMID: 11152400

7

Pharmacokinetic parameters and mechanisms of inhibition of rat type 1 and 2 steroid 5alpha-reductases: determinants for different in vivo activities of GI198745 and finasteride in the rat.

Stuart JD, Lee FW, Simpson Noel D, Kadwell SH, Overton LK, Hoffman CR, Kost TA, Tippin TK, Yeager RL, Batchelor KW, Bramson HN. Stuart JD, et al. Among authors: kadwell sh. Biochem Pharmacol. 2001 Oct 1;62(7):933-42. doi: 10.1016/s0006-2952(01)00728-6. Biochem Pharmacol. 2001. PMID: 11543729

8

Agouti protein is an antagonist of the melanocyte-stimulating-hormone receptor.

Lu D, Willard D, Patel IR, Kadwell S, Overton L, Kost T, Luther M, Chen W, Woychik RP, Wilkison WO, et al. Lu D, et al. Nature. 1994 Oct 27;371(6500):799-802. doi: 10.1038/371799a0. Nature. 1994. PMID: 7935841

9

Comparison of the biochemical and kinetic properties of the type 1 receptor tyrosine kinase intracellular domains. Demonstration of differential sensitivity to kinase inhibitors.

Brignola PS, Lackey K, Kadwell SH, Hoffman C, Horne E, Carter HL, Stuart JD, Blackburn K, Moyer MB, Alligood KJ, Knight WB, Wood ER. Brignola PS, et al. Among authors: kadwell sh. J Biol Chem. 2002 Jan 11;277(2):1576-85. doi: 10.1074/jbc.M105907200. Epub 2001 Nov 5. J Biol Chem. 2002. PMID: 11696537 Free article.

10

CYP3A4 expressed by insect cells infected with a recombinant baculovirus containing both CYP3A4 and human NADPH-cytochrome P450 reductase is catalytically similar to human liver microsomal CYP3A4.

Lee CA, Kadwell SH, Kost TA, Serabjit-Singh CJ. Lee CA, et al. Among authors: kadwell sh. Arch Biochem Biophys. 1995 May 10;319(1):157-67. doi: 10.1006/abbi.1995.1278. Arch Biochem Biophys. 1995. PMID: 7771780

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