Hu P - Search Results

1

Biotransformation of the naturally occurring isothiocyanate sulforaphane in the rat: identification of phase I metabolites and glutathione conjugates.

Kassahun K, Davis M, Hu P, Martin B, Baillie T. Kassahun K, et al. Among authors: hu p. Chem Res Toxicol. 1997 Nov;10(11):1228-33. doi: 10.1021/tx970080t. Chem Res Toxicol. 1997. PMID: 9403174

2

Identification of novel glutathione conjugates of disulfiram and diethyldithiocarbamate in rat bile by liquid chromatography-tandem mass spectrometry. Evidence for metabolic activation of disulfiram in vivo.

Jin L, Davis MR, Hu P, Baillie TA. Jin L, et al. Among authors: hu p. Chem Res Toxicol. 1994 Jul-Aug;7(4):526-33. doi: 10.1021/tx00040a008. Chem Res Toxicol. 1994. PMID: 7981417

3

Metabolic activation of unsaturated derivatives of valproic acid. Identification of novel glutathione adducts formed through coenzyme A-dependent and -independent processes.

Kassahun K, Hu P, Grillo MP, Davis MR, Jin L, Baillie TA. Kassahun K, et al. Among authors: hu p. Chem Biol Interact. 1994 Mar;90(3):253-75. doi: 10.1016/0009-2797(94)90014-0. Chem Biol Interact. 1994. PMID: 8168173

4

Studies on the metabolic activation of disulfiram in rat. Evidence for electrophilic S-oxygenated metabolites as inhibitors of aldehyde dehydrogenase and precursors of urinary N-acetylcysteine conjugates.

Hu P, Jin L, Baillie TA. Hu P, et al. J Pharmacol Exp Ther. 1997 May;281(2):611-7. J Pharmacol Exp Ther. 1997. PMID: 9152363

5

Stereochemical studies on the beta-oxidation of valproic acid in isolated rat hepatocytes.

Shirley MA, Hu P, Baillie TA. Shirley MA, et al. Among authors: hu p. Drug Metab Dispos. 1993 Jul-Aug;21(4):580-6. Drug Metab Dispos. 1993. PMID: 8104116

6

Unexpected deacetylation mechanism suggested by a density functional theory QM/MM study of histone-deacetylase-like protein.

Corminboeuf C, Hu P, Tuckerman ME, Zhang Y. Corminboeuf C, et al. Among authors: hu p. J Am Chem Soc. 2006 Apr 12;128(14):4530-1. doi: 10.1021/ja0600882. J Am Chem Soc. 2006. PMID: 16594663

7

Catalytic mechanism and product specificity of the histone lysine methyltransferase SET7/9: an ab initio QM/MM-FE study with multiple initial structures.

Hu P, Zhang Y. Hu P, et al. J Am Chem Soc. 2006 Feb 1;128(4):1272-8. doi: 10.1021/ja056153+. J Am Chem Soc. 2006. PMID: 16433545

8

Highly dissociative and concerted mechanism for the nicotinamide cleavage reaction in Sir2Tm enzyme suggested by ab initio QM/MM molecular dynamics simulations.

Hu P, Wang S, Zhang Y. Hu P, et al. J Am Chem Soc. 2008 Dec 10;130(49):16721-8. doi: 10.1021/ja807269j. J Am Chem Soc. 2008. PMID: 19049465 Free PMC article.

9

How do SET-domain protein lysine methyltransferases achieve the methylation state specificity? Revisited by Ab initio QM/MM molecular dynamics simulations.

Hu P, Wang S, Zhang Y. Hu P, et al. J Am Chem Soc. 2008 Mar 26;130(12):3806-13. doi: 10.1021/ja075896n. Epub 2008 Mar 1. J Am Chem Soc. 2008. PMID: 18311969 Free PMC article.

10

Tuning the membrane selectivity of antimicrobial peptides by using multivalent design.

Liu Z, Young AW, Hu P, Rice AJ, Zhou C, Zhang Y, Kallenbach NR. Liu Z, et al. Among authors: hu p. Chembiochem. 2007 Nov 23;8(17):2063-5. doi: 10.1002/cbic.200700502. Chembiochem. 2007. PMID: 17924379 No abstract available.

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