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Targeting the ACOD1-itaconate axis stabilizes atherosclerotic plaques.
Harber KJ, Neele AE, van Roomen CP, Gijbels MJ, Beckers L, Toom MD, Schomakers BV, Heister DA, Willemsen L, Griffith GR, de Goede KE, van Dierendonck XA, Reiche ME, Poli A, L-H Mogensen F, Michelucci A, Verberk SG, de Vries H, van Weeghel M, Van den Bossche J, de Winther MP. Harber KJ, et al. Among authors: griffith gr. Redox Biol. 2024 Apr;70:103054. doi: 10.1016/j.redox.2024.103054. Epub 2024 Jan 22. Redox Biol. 2024. PMID: 38309122 Free PMC article.
Identification of new drugs to counteract anti-spike IgG-induced hyperinflammation in severe COVID-19.
Geyer CE, Chen HJ, Bye AP, Manz XD, Guerra D, Caniels TG, Bijl TP, Griffith GR, Hoepel W, de Taeye SW, Veth J, Vlaar AP; Amsterdam UMC COVID-19 Biobank; Vidarsson G, Bogaard HJ, Aman J, Gibbins JM, van Gils MJ, de Winther MP, den Dunnen J. Geyer CE, et al. Among authors: griffith gr. Life Sci Alliance. 2023 Sep 12;6(11):e202302106. doi: 10.26508/lsa.202302106. Print 2023 Nov. Life Sci Alliance. 2023. PMID: 37699657 Free PMC article.
DOT1L regulates lipid biosynthesis and inflammatory responses in macrophages and promotes atherosclerotic plaque stability.
Willemsen L, Prange KHM, Neele AE, van Roomen CPAA, Gijbels M, Griffith GR, Toom MD, Beckers L, Siebeler R, Spann NJ, Chen HJ, Bosmans LA, Gorbatenko A, van Wouw S, Zelcer N, Jacobs H, van Leeuwen F, de Winther MPJ. Willemsen L, et al. Among authors: griffith gr. Cell Rep. 2022 Nov 22;41(8):111703. doi: 10.1016/j.celrep.2022.111703. Cell Rep. 2022. PMID: 36417856 Free article.
C-Reactive Protein Controls IL-23 Production by Human Monocytes.
Geyer CE, Newling M, Sritharan L, Griffith GR, Chen HJ, Baeten DLP, den Dunnen J. Geyer CE, et al. Among authors: griffith gr. Int J Mol Sci. 2021 Oct 28;22(21):11638. doi: 10.3390/ijms222111638. Int J Mol Sci. 2021. PMID: 34769069 Free PMC article.
25 results