Spratt TE - Search Results

1

Stereochemistry of the in vitro and in vivo methylation of DNA by (R)- and (S)-N-[2H1,3H]methyl-N-nitrosourea and (R)- and (S)-N-nitroso-N-[2H1,3H]methyl-N-methylamine.

Spratt TE, Zydowsky TM, Floss HG. Spratt TE, et al. Chem Res Toxicol. 1997 Dec;10(12):1412-9. doi: 10.1021/tx970097b. Chem Res Toxicol. 1997. PMID: 9437533

2

Honokiol Inhibits DNA Polymerases β and λ and Increases Bleomycin Sensitivity of Human Cancer Cells.

Gowda AS, Suo Z, Spratt TE. Gowda AS, et al. Among authors: spratt te. Chem Res Toxicol. 2017 Feb 20;30(2):715-725. doi: 10.1021/acs.chemrestox.6b00451. Epub 2017 Jan 19. Chem Res Toxicol. 2017. PMID: 28067485 Free PMC article.

3

Differences in the rate of repair of O6-alkylguanines in different sequence contexts by O6-alkylguanine-DNA alkyltransferase.

Coulter R, Blandino M, Tomlinson JM, Pauly GT, Krajewska M, Moschel RC, Peterson LA, Pegg AE, Spratt TE. Coulter R, et al. Among authors: spratt te. Chem Res Toxicol. 2007 Dec;20(12):1966-71. doi: 10.1021/tx700271j. Epub 2007 Nov 1. Chem Res Toxicol. 2007. PMID: 17975884

4

Facile syntheses of O(2)-[4-(3-pyridyl-4-oxobut-1-yl]thymidine, the major adduct formed by tobacco specific nitrosamine 4-methylnitrosamino-1-(3-pyridyl)-1-butanone (NNK) in vivo, and its site-specifically adducted oligodeoxynucleotides.

Krishnegowda G, Sharma AK, Krzeminski J, Gowda AS, Lin JM, Desai D, Spratt TE, Amin S. Krishnegowda G, et al. Among authors: spratt te. Chem Res Toxicol. 2011 Jun 20;24(6):960-7. doi: 10.1021/tx200127j. Epub 2011 May 5. Chem Res Toxicol. 2011. PMID: 21524094 Free PMC article.

5

Tobacco-specific nitrosamine-derived O2-alkylthymidines are potent mutagenic lesions in SOS-induced Escherichia coli.

Jasti VP, Spratt TE, Basu AK. Jasti VP, et al. Among authors: spratt te. Chem Res Toxicol. 2011 Nov 21;24(11):1833-5. doi: 10.1021/tx200435d. Epub 2011 Oct 28. Chem Res Toxicol. 2011. PMID: 22029400 Free PMC article.

6

DNA Polymerase ν Rapidly Bypasses O⁶-Methyl-dG but Not O⁶-[4-(3-Pyridyl)-4-oxobutyl-dG and O²-Alkyl-dTs.

Gowda AS, Spratt TE. Gowda AS, et al. Among authors: spratt te. Chem Res Toxicol. 2016 Nov 21;29(11):1894-1900. doi: 10.1021/acs.chemrestox.6b00318. Epub 2016 Oct 25. Chem Res Toxicol. 2016. PMID: 27741574 Free PMC article.

7

Mutagenic Replication of N²-Deoxyguanosine Benzo[a]pyrene Adducts by Escherichia coli DNA Polymerase I and Sulfolobus solfataricus DNA Polymerase IV.

Gowda ASP, Krzeminski J, Amin S, Suo Z, Spratt TE. Gowda ASP, et al. Among authors: spratt te. Chem Res Toxicol. 2017 May 15;30(5):1168-1176. doi: 10.1021/acs.chemrestox.6b00466. Epub 2017 Apr 19. Chem Res Toxicol. 2017. PMID: 28402640 Free PMC article.

8

Active Site Interactions Impact Phosphoryl Transfer during Replication of Damaged and Undamaged DNA by Escherichia coli DNA Polymerase I.

Prakasha Gowda AS, Spratt TE. Prakasha Gowda AS, et al. Among authors: spratt te. Chem Res Toxicol. 2017 Nov 20;30(11):2033-2043. doi: 10.1021/acs.chemrestox.7b00257. Epub 2017 Oct 25. Chem Res Toxicol. 2017. PMID: 29053918 Free PMC article.

9

Characterization of dibenzo[a,l]pyrene-trans-11,12-diol (dibenzo[def,p]chrysene) glucuronidation by UDP-glucuronosyltransferases.

Olson KC, Sun D, Chen G, Sharma AK, Amin S, Ropson IJ, Spratt TE, Lazarus P. Olson KC, et al. Among authors: spratt te. Chem Res Toxicol. 2011 Sep 19;24(9):1549-59. doi: 10.1021/tx200178v. Epub 2011 Aug 5. Chem Res Toxicol. 2011. PMID: 21780761 Free PMC article.

10

Low fidelity bypass of O(2)-(3-pyridyl)-4-oxobutylthymine, the most persistent bulky adduct produced by the tobacco specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by model DNA polymerases.

Gowda AS, Krishnegowda G, Suo Z, Amin S, Spratt TE. Gowda AS, et al. Among authors: spratt te. Chem Res Toxicol. 2012 Jun 18;25(6):1195-202. doi: 10.1021/tx200483g. Epub 2012 May 1. Chem Res Toxicol. 2012. PMID: 22533615

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