Okamoto I - Search Results

1

Expression of CD44 splicing isoforms in lung cancers: dominant expression of CD44v8-10 in non-small cell lung carcinomas.

Sasaki JI, Tanabe KK, Takahashi K, Okamoto I, Fujimoto H, Matsumoto M, Suga M, Ando M, Saya H. Sasaki JI, et al. Among authors: okamoto i. Int J Oncol. 1998 Mar;12(3):525-33. doi: 10.3892/ijo.12.3.525. Int J Oncol. 1998. PMID: 9472088

2

Molecular detection of cancer cells by competitive reverse transcription-polymerase chain reaction analysis of specific CD44 variant RNAs.

Okamoto I, Morisaki T, Sasaki J, Miyake H, Matsumoto M, Suga M, Ando M, Saya H. Okamoto I, et al. J Natl Cancer Inst. 1998 Feb 18;90(4):307-15. doi: 10.1093/jnci/90.4.307. J Natl Cancer Inst. 1998. PMID: 9486817

3

Interaction between CD44 and hyaluronic acid regulates human prostate cancer development.

Miyake H, Hara I, Okamoto I, Gohji K, Yamanaka K, Arakawa S, Saya H, Kamidono S. Miyake H, et al. Among authors: okamoto i. J Urol. 1998 Oct;160(4):1562-6. J Urol. 1998. PMID: 9751413

4

Highly specific and sensitive detection of malignancy in urine samples from patients with urothelial cancer by CD44v8-10/CD44v10 competitive RT-PCR.

Miyake H, Okamoto I, Hara I, Gohji K, Yamanaka K, Arakawa S, Kamidono S, Saya H. Miyake H, et al. Among authors: okamoto i. Int J Cancer. 1998 Dec 18;79(6):560-4. doi: 10.1002/(sici)1097-0215(19981218)79:6<560::aid-ijc2>3.0.co;2-x. Int J Cancer. 1998. PMID: 9842962

5

CD44 cleavage induced by a membrane-associated metalloprotease plays a critical role in tumor cell migration.

Okamoto I, Kawano Y, Tsuiki H, Sasaki J, Nakao M, Matsumoto M, Suga M, Ando M, Nakajima M, Saya H. Okamoto I, et al. Oncogene. 1999 Feb 18;18(7):1435-46. doi: 10.1038/sj.onc.1202447. Oncogene. 1999. PMID: 10050880

6

Regulated CD44 cleavage under the control of protein kinase C, calcium influx, and the Rho family of small G proteins.

Okamoto I, Kawano Y, Matsumoto M, Suga M, Kaibuchi K, Ando M, Saya H. Okamoto I, et al. J Biol Chem. 1999 Sep 3;274(36):25525-34. doi: 10.1074/jbc.274.36.25525. J Biol Chem. 1999. PMID: 10464284 Free article.

Our previous studies have shown that CD44 expressed in cancer cells is proteolytically cleaved at the extracellular domain through membrane-associated metalloproteases and that CD44 cleavage plays a critical role in CD44-mediated tumor cell migration (Okamoto, I., K …

Our previous studies have shown that CD44 expressed in cancer cells is proteolytically cleaved at the extracellular domain through membrane- …

7

Calcium influx triggers the sequential proteolysis of extracellular and cytoplasmic domains of E-cadherin, leading to loss of beta-catenin from cell-cell contacts.

Ito K, Okamoto I, Araki N, Kawano Y, Nakao M, Fujiyama S, Tomita K, Mimori T, Saya H. Ito K, et al. Among authors: okamoto i. Oncogene. 1999 Nov 25;18(50):7080-90. doi: 10.1038/sj.onc.1203191. Oncogene. 1999. PMID: 10597309

8

Ras oncoprotein induces CD44 cleavage through phosphoinositide 3-OH kinase and the rho family of small G proteins.

Kawano Y, Okamoto I, Murakami D, Itoh H, Yoshida M, Ueda S, Saya H. Kawano Y, et al. Among authors: okamoto i. J Biol Chem. 2000 Sep 22;275(38):29628-35. doi: 10.1074/jbc.M002440200. J Biol Chem. 2000. PMID: 10896935 Free article.

9

Proteolytic release of CD44 intracellular domain and its role in the CD44 signaling pathway.

Okamoto I, Kawano Y, Murakami D, Sasayama T, Araki N, Miki T, Wong AJ, Saya H. Okamoto I, et al. J Cell Biol. 2001 Nov 26;155(5):755-62. doi: 10.1083/jcb.200108159. Epub 2001 Nov 19. J Cell Biol. 2001. PMID: 11714729 Free PMC article.

10

Proteolytic cleavage of the CD44 adhesion molecule in multiple human tumors.

Okamoto I, Tsuiki H, Kenyon LC, Godwin AK, Emlet DR, Holgado-Madruga M, Lanham IS, Joynes CJ, Vo KT, Guha A, Matsumoto M, Ushio Y, Saya H, Wong AJ. Okamoto I, et al. Am J Pathol. 2002 Feb;160(2):441-7. doi: 10.1016/S0002-9440(10)64863-8. Am J Pathol. 2002. PMID: 11839564 Free PMC article.

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