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Design, synthesis, and pharmacological evaluation of conformationally constrained analogues of N,N'-diaryl- and N-aryl-N-aralkylguanidines as potent inhibitors of neuronal Na+ channels.
Maillard MC, Perlman ME, Amitay O, Baxter D, Berlove D, Connaughton S, Fischer JB, Guo JQ, Hu LY, McBurney RN, Nagy PI, Subbarao K, Yost EA, Zhang L, Durant GJ. Maillard MC, et al. Among authors: amitay o. J Med Chem. 1998 Jul 30;41(16):3048-61. doi: 10.1021/jm980124a. J Med Chem. 1998. PMID: 9685245