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Page 1
A rapid method for simultaneous detection of phenotypic resistance to inhibitors of protease and reverse transcriptase in recombinant human immunodeficiency virus type 1 isolates from patients treated with antiretroviral drugs.
Hertogs K, de Béthune MP, Miller V, Ivens T, Schel P, Van Cauwenberge A, Van Den Eynde C, Van Gerwen V, Azijn H, Van Houtte M, Peeters F, Staszewski S, Conant M, Bloor S, Kemp S, Larder B, Pauwels R. Hertogs K, et al. Among authors: azijn h. Antimicrob Agents Chemother. 1998 Feb;42(2):269-76. doi: 10.1128/AAC.42.2.269. Antimicrob Agents Chemother. 1998. PMID: 9527771 Free PMC article.
TMC125, a novel next-generation nonnucleoside reverse transcriptase inhibitor active against nonnucleoside reverse transcriptase inhibitor-resistant human immunodeficiency virus type 1.
Andries K, Azijn H, Thielemans T, Ludovici D, Kukla M, Heeres J, Janssen P, De Corte B, Vingerhoets J, Pauwels R, de Béthune MP. Andries K, et al. Among authors: azijn h. Antimicrob Agents Chemother. 2004 Dec;48(12):4680-6. doi: 10.1128/AAC.48.12.4680-4686.2004. Antimicrob Agents Chemother. 2004. PMID: 15561844 Free PMC article.
TMC114, a novel human immunodeficiency virus type 1 protease inhibitor active against protease inhibitor-resistant viruses, including a broad range of clinical isolates.
De Meyer S, Azijn H, Surleraux D, Jochmans D, Tahri A, Pauwels R, Wigerinck P, de Béthune MP. De Meyer S, et al. Among authors: azijn h. Antimicrob Agents Chemother. 2005 Jun;49(6):2314-21. doi: 10.1128/AAC.49.6.2314-2321.2005. Antimicrob Agents Chemother. 2005. PMID: 15917527 Free PMC article.
Inhibition of human immunodeficiency virus type 1 infection by the candidate microbicide dapivirine, a nonnucleoside reverse transcriptase inhibitor.
Fletcher P, Harman S, Azijn H, Armanasco N, Manlow P, Perumal D, de Bethune MP, Nuttall J, Romano J, Shattock R. Fletcher P, et al. Among authors: azijn h. Antimicrob Agents Chemother. 2009 Feb;53(2):487-95. doi: 10.1128/AAC.01156-08. Epub 2008 Nov 24. Antimicrob Agents Chemother. 2009. PMID: 19029331 Free PMC article.
Design, synthesis, and SAR of a novel pyrazinone series with non-nucleoside HIV-1 reverse transcriptase inhibitory activity.
Heeres J, de Jonge MR, Koymans LM, Daeyaert FF, Vinkers M, Van Aken KJ, Arnold E, Das K, Kilonda A, Hoornaert GJ, Compernolle F, Cegla M, Azzam RA, Andries K, de Béthune MP, Azijn H, Pauwels R, Lewi PJ, Janssen PA. Heeres J, et al. Among authors: azijn h. J Med Chem. 2005 Mar 24;48(6):1910-8. doi: 10.1021/jm040829e. J Med Chem. 2005. PMID: 15771435
Design of HIV-1 protease inhibitors active on multidrug-resistant virus.
Surleraux DL, de Kock HA, Verschueren WG, Pille GM, Maes LJ, Peeters A, Vendeville S, De Meyer S, Azijn H, Pauwels R, de Bethune MP, King NM, Prabu-Jeyabalan M, Schiffer CA, Wigerinck PB. Surleraux DL, et al. Among authors: azijn h. J Med Chem. 2005 Mar 24;48(6):1965-73. doi: 10.1021/jm049454n. J Med Chem. 2005. PMID: 15771440
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