Young SG - Search Results

1

Construction of two near-kilobase resolution restriction maps of the 5' regulatory region of the human apolipoprotein B gene by quantitative DNA fiber mapping (QDFM).

Duell T, Nielsen LB, Jones A, Young SG, Weier HU. Duell T, et al. Among authors: young sg. Cytogenet Cell Genet. 1997;79(1-2):64-70. doi: 10.1159/000134685. Cytogenet Cell Genet. 1997. PMID: 9533015

2

Human apolipoprotein B transgenic mice generated with 207- and 145-kilobase pair bacterial artificial chromosomes. Evidence that a distant 5'-element confers appropriate transgene expression in the intestine.

Nielsen LB, McCormick SP, Pierotti V, Tam C, Gunn MD, Shizuya H, Young SG. Nielsen LB, et al. Among authors: young sg. J Biol Chem. 1997 Nov 21;272(47):29752-8. doi: 10.1074/jbc.272.47.29752. J Biol Chem. 1997. PMID: 9368045 Free article.

3

Genes for apolipoprotein B and microsomal triglyceride transfer protein are expressed in the heart: evidence that the heart has the capacity to synthesize and secrete lipoproteins.

Nielsen LB, Véniant M, Borén J, Raabe M, Wong JS, Tam C, Flynn L, Vanni-Reyes T, Gunn MD, Goldberg IJ, Hamilton RL, Young SG. Nielsen LB, et al. Among authors: young sg. Circulation. 1998 Jul 7;98(1):13-6. doi: 10.1161/01.cir.98.1.13. Circulation. 1998. PMID: 9665054

4

Apolipoprotein B gene expression in a series of human apolipoprotein B transgenic mice generated with recA-assisted restriction endonuclease cleavage-modified bacterial artificial chromosomes. An intestine-specific enhancer element is located between 54 and 62 kilobases 5' to the structural gene.

Nielsen LB, Kahn D, Duell T, Weier HU, Taylor S, Young SG. Nielsen LB, et al. Among authors: young sg. J Biol Chem. 1998 Aug 21;273(34):21800-7. doi: 10.1074/jbc.273.34.21800. J Biol Chem. 1998. PMID: 9705318 Free article.

5

Chylomicron-sized lipid particles are formed in the setting of apolipoprotein B deficiency.

Hamilton RL, Wong JS, Cham CM, Nielsen LB, Young SG. Hamilton RL, et al. Among authors: young sg. J Lipid Res. 1998 Aug;39(8):1543-57. J Lipid Res. 1998. PMID: 9717714 Free article.

6

Using genetically engineered mice to understand apolipoprotein-B deficiency syndromes in humans.

Raabe M, Kim E, Véniant M, Nielsen LB, Young SG. Raabe M, et al. Among authors: young sg. Proc Assoc Am Physicians. 1998 Nov-Dec;110(6):521-30. Proc Assoc Am Physicians. 1998. PMID: 9824535 Review.

7

Insights into apolipoprotein B biology from transgenic and gene-targeted mice.

Véniant MM, Kim E, McCormick S, Borén J, Nielsen LB, Raabe M, Young SG. Véniant MM, et al. Among authors: young sg. J Nutr. 1999 Feb;129(2S Suppl):451S-455S. doi: 10.1093/jn/129.2.451S. J Nutr. 1999. PMID: 10064308 Review.

8

A new approach for studying gene regulation by distant DNA elements in transgenic mice.

Nielsen LB, McCormick SP, Young SG. Nielsen LB, et al. Among authors: young sg. Scand J Clin Lab Invest Suppl. 1999;229:33-9. doi: 10.1080/00365519950185931. Scand J Clin Lab Invest Suppl. 1999. PMID: 10097288 Review.

9

The DNA sequences required for apolipoprotein B expression in the heart are distinct from those required for expression in the intestine.

Nielsen LB, Sullivan M, Vanni-Reyes T, Goldberg IJ, Young SG. Nielsen LB, et al. Among authors: young sg. J Mol Cell Cardiol. 1999 Apr;31(4):695-703. doi: 10.1006/jmcc.1998.0918. J Mol Cell Cardiol. 1999. PMID: 10329198

10

Lipoproteins containing apolipoprotein B-100 are secreted by the heart.

Véniant MM, Nielsen LB, Borén J, Young SG. Véniant MM, et al. Among authors: young sg. Trends Cardiovasc Med. 1999 Apr-May;9(3-4):103-7. doi: 10.1016/s1050-1738(99)00011-0. Trends Cardiovasc Med. 1999. PMID: 10578525 Review.

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