Kirkham D - Search Results

1

Late-onset neurodegeneration in mice with increased dosage of the proteolipid protein gene.

Anderson TJ, Schneider A, Barrie JA, Klugmann M, McCulloch MC, Kirkham D, Kyriakides E, Nave KA, Griffiths IR. Anderson TJ, et al. Among authors: kirkham d. J Comp Neurol. 1998 May 18;394(4):506-19. doi: 10.1002/(sici)1096-9861(19980518)394:4<506::aid-cne8>3.0.co;2-5. J Comp Neurol. 1998. PMID: 9590558

2

PLP overexpression perturbs myelin protein composition and myelination in a mouse model of Pelizaeus-Merzbacher disease.

Karim SA, Barrie JA, McCulloch MC, Montague P, Edgar JM, Kirkham D, Anderson TJ, Nave KA, Griffiths IR, McLaughlin M. Karim SA, et al. Among authors: kirkham d. Glia. 2007 Mar;55(4):341-51. doi: 10.1002/glia.20465. Glia. 2007. PMID: 17133418

3

Genetic background determines phenotypic severity of the Plp rumpshaker mutation.

Al-Saktawi K, McLaughlin M, Klugmann M, Schneider A, Barrie JA, McCulloch MC, Montague P, Kirkham D, Nave KA, Griffiths IR. Al-Saktawi K, et al. Among authors: kirkham d. J Neurosci Res. 2003 Apr 1;72(1):12-24. doi: 10.1002/jnr.10561. J Neurosci Res. 2003. PMID: 12645075

4

Processing of PLP in a model of Pelizaeus-Merzbacher disease/SPG2 due to the rumpshaker mutation.

McLaughlin M, Barrie JA, Karim S, Montague P, Edgar JM, Kirkham D, Thomson CE, Griffiths IR. McLaughlin M, et al. Among authors: kirkham d. Glia. 2006 May;53(7):715-22. doi: 10.1002/glia.20325. Glia. 2006. PMID: 16506223

5

Modulation of rumpshaker phenotype with wild-type PLP/DM20 suggests several pathogenic mechanisms.

Barrie JA, Montague P, Karim S, Kirkham D, Nave KA, Anderson TJ, Griffiths IR, McLaughlin M. Barrie JA, et al. Among authors: kirkham d. J Neurosci Res. 2010 Aug 1;88(10):2135-45. doi: 10.1002/jnr.22379. J Neurosci Res. 2010. PMID: 20175203

6

Expression of myelin protein gene transcripts by Schwann cells of regenerating nerve.

Mitchell LS, Griffiths IR, Morrison S, Barrie JA, Kirkham D, McPhilemy K. Mitchell LS, et al. Among authors: kirkham d. J Neurosci Res. 1990 Oct;27(2):125-35. doi: 10.1002/jnr.490270202. J Neurosci Res. 1990. PMID: 1701490

7

P0 gene expression in cultured Schwann cells.

Morrison S, Mitchell LS, Ecob-Prince MS, Griffiths IR, Thomson CE, Barrie JA, Kirkham D. Morrison S, et al. Among authors: kirkham d. J Neurocytol. 1991 Sep;20(9):769-80. doi: 10.1007/BF01187850. J Neurocytol. 1991. PMID: 1720451

8

Reduced levels of a specific myelin-associated oligodendrocytic basic protein isoform in shiverer myelin.

Montague P, Kirkham D, McCallion AS, Davies RW, Kennedy PG, Klugmann M, Nave K, Griffiths IR. Montague P, et al. Among authors: kirkham d. Dev Neurosci. 1999;21(1):36-42. doi: 10.1159/000017364. Dev Neurosci. 1999. PMID: 10077700

9

Evidence for possible interactions between PLP and DM20 within the myelin sheath.

McLaughlin M, Hunter DJ, Thomson CE, Yool D, Kirkham D, Freer AA, Griffiths IR. McLaughlin M, et al. Among authors: kirkham d. Glia. 2002 Jul;39(1):31-6. doi: 10.1002/glia.10091. Glia. 2002. PMID: 12112373

10

Genetic background influences UPR but not PLP processing in the rumpshaker model of PMD/SPG2.

McLaughlin M, Karim SA, Montague P, Barrie JA, Kirkham D, Griffiths IR, Edgar JM. McLaughlin M, et al. Among authors: kirkham d. Neurochem Res. 2007 Feb;32(2):167-76. doi: 10.1007/s11064-006-9122-y. Epub 2006 Aug 31. Neurochem Res. 2007. PMID: 16944321

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