Crews BC - Search Results

1

Aspirin-like molecules that covalently inactivate cyclooxygenase-2.

Kalgutkar AS, Crews BC, Rowlinson SW, Garner C, Seibert K, Marnett LJ. Kalgutkar AS, et al. Among authors: crews bc. Science. 1998 May 22;280(5367):1268-70. doi: 10.1126/science.280.5367.1268. Science. 1998. PMID: 9596581

2

Design, synthesis, and biochemical evaluation of N-substituted maleimides as inhibitors of prostaglandin endoperoxide synthases.

Kalgutkar AS, Crews BC, Marnett LJ. Kalgutkar AS, et al. Among authors: crews bc. J Med Chem. 1996 Apr 12;39(8):1692-703. doi: 10.1021/jm950872p. J Med Chem. 1996. PMID: 8648609

3

Kinetics of the interaction of nonsteroidal antiinflammatory drugs with prostaglandin endoperoxide synthase-1 studied by limited proteolysis.

Kalgutkar AS, Crews BC, Marnett LJ. Kalgutkar AS, et al. Among authors: crews bc. Biochemistry. 1996 Jul 16;35(28):9076-82. doi: 10.1021/bi9605752. Biochemistry. 1996. PMID: 8703911

4

Peroxynitrite, the coupling product of nitric oxide and superoxide, activates prostaglandin biosynthesis.

Landino LM, Crews BC, Timmons MD, Morrow JD, Marnett LJ. Landino LM, et al. Among authors: crews bc. Proc Natl Acad Sci U S A. 1996 Dec 24;93(26):15069-74. doi: 10.1073/pnas.93.26.15069. Proc Natl Acad Sci U S A. 1996. PMID: 8986765 Free PMC article.

5

Mutational analysis of the role of the distal histidine and glutamine residues of prostaglandin-endoperoxide synthase-2 in peroxidase catalysis, hydroperoxide reduction, and cyclooxygenase activation.

Landino LM, Crews BC, Gierse JK, Hauser SD, Marnett LJ. Landino LM, et al. Among authors: crews bc. J Biol Chem. 1997 Aug 22;272(34):21565-74. doi: 10.1074/jbc.272.34.21565. J Biol Chem. 1997. PMID: 9261177 Free article.

6

Inactivation of prostaglandin endoperoxide synthase (PGHS) by N-(substituted)maleimides.

Kalgutkar AS, Crews BC, Marnett LJ. Kalgutkar AS, et al. Among authors: crews bc. Adv Exp Med Biol. 1997;407:79-85. doi: 10.1007/978-1-4899-1813-0_12. Adv Exp Med Biol. 1997. PMID: 9321935 No abstract available.

7

Nitric oxide trapping of tyrosyl radicals generated during prostaglandin endoperoxide synthase turnover. Detection of the radical derivative of tyrosine 385.

Goodwin DC, Gunther MR, Hsi LC, Crews BC, Eling TE, Mason RP, Marnett LJ. Goodwin DC, et al. Among authors: crews bc. J Biol Chem. 1998 Apr 10;273(15):8903-9. doi: 10.1074/jbc.273.15.8903. J Biol Chem. 1998. PMID: 9535872 Free article.

8

Covalent modification of cyclooxygenase-2 (COX-2) by 2-acetoxyphenyl alkyl sulfides, a new class of selective COX-2 inactivators.

Kalgutkar AS, Kozak KR, Crews BC, Hochgesang GP Jr, Marnett LJ. Kalgutkar AS, et al. Among authors: crews bc. J Med Chem. 1998 Nov 19;41(24):4800-18. doi: 10.1021/jm980303s. J Med Chem. 1998. PMID: 9822550

9

The binding of arachidonic acid in the cyclooxygenase active site of mouse prostaglandin endoperoxide synthase-2 (COX-2). A putative L-shaped binding conformation utilizing the top channel region.

Rowlinson SW, Crews BC, Lanzo CA, Marnett LJ. Rowlinson SW, et al. Among authors: crews bc. J Biol Chem. 1999 Aug 13;274(33):23305-10. doi: 10.1074/jbc.274.33.23305. J Biol Chem. 1999. PMID: 10438506 Free article.

10

Thromboxane A2 is a mediator of cyclooxygenase-2-dependent endothelial migration and angiogenesis.

Daniel TO, Liu H, Morrow JD, Crews BC, Marnett LJ. Daniel TO, et al. Among authors: crews bc. Cancer Res. 1999 Sep 15;59(18):4574-7. Cancer Res. 1999. PMID: 10493510

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