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Pituitary adenylate cyclase-activating polypeptide (PACAP) is a regulator of astrocytes: PACAP stimulates proliferation and production of interleukin 6 (IL-6), but not nerve growth factor (NGF), in cultured rat astrocyte.
Tatsuno I, Morio H, Tanaka T, Uchida D, Hirai A, Tamura Y, Saito Y. Tatsuno I, et al. Among authors: hirai a. Ann N Y Acad Sci. 1996 Dec 26;805:482-8. doi: 10.1111/j.1749-6632.1996.tb17508.x. Ann N Y Acad Sci. 1996. PMID: 8993428 No abstract available.
Astrocytes are one of the main target cells for pituitary adenylate cyclase-activating polypeptide in the central nervous system. Astrocytes are very heterogeneous regarding both basal movement of intracellular free calcium ([Ca2+]i) and the [Ca2+]i response to PACAP at a single cell level.
Tatsuno I, Morio H, Tanaka T, Hirai A, Tamura Y, Saito Y, Arimura A. Tatsuno I, et al. Among authors: hirai a. Ann N Y Acad Sci. 1996 Dec 26;805:613-9. doi: 10.1111/j.1749-6632.1996.tb17529.x. Ann N Y Acad Sci. 1996. PMID: 8993449 No abstract available.
Activation of cyclin-dependent kinase 2 (Cdk2) in growth-stimulated rat astrocytes. Geranylgeranylated Rho small GTPase(s) are essential for the induction of cyclin E gene expression.
Tanaka T, Tatsuno I, Noguchi Y, Uchida D, Oeda T, Narumiya S, Yasuda T, Higashi H, Kitagawa M, Nakayama K, Saito Y, Hirai A. Tanaka T, et al. Among authors: hirai a. J Biol Chem. 1998 Oct 9;273(41):26772-8. doi: 10.1074/jbc.273.41.26772. J Biol Chem. 1998. PMID: 9756921 Free article.
519 results