Kirken RA - Search Results

1

Differential regulation of the Janus kinase-STAT pathway and biologic function of IL-13 in primary human NK and T cells: a comparative study with IL-4.

Yu CR, Kirken RA, Malabarba MG, Young HA, Ortaldo JR. Yu CR, et al. Among authors: kirken ra. J Immunol. 1998 Jul 1;161(1):218-27. J Immunol. 1998. PMID: 9647227

2

JAK3, STAT, and MAPK signaling pathways as novel molecular targets for the tyrphostin AG-490 regulation of IL-2-mediated T cell response.

Wang LH, Kirken RA, Erwin RA, Yu CR, Farrar WL. Wang LH, et al. Among authors: kirken ra. J Immunol. 1999 Apr 1;162(7):3897-904. J Immunol. 1999. PMID: 10201908

3

Identification of a Stat-6-responsive element in the promoter of the human interleukin-4 gene.

Curiel RE, Lahesmaa R, Subleski J, Cippitelli M, Kirken RA, Young HA, Ghosh P. Curiel RE, et al. Among authors: kirken ra. Eur J Immunol. 1997 Aug;27(8):1982-7. doi: 10.1002/eji.1830270823. Eur J Immunol. 1997. PMID: 9295035

4

Coactivation of janus tyrosine kinase (Jak)1 positively modulates prolactin-Jak2 signaling in breast cancer: recruitment of ERK and signal transducer and activator of transcription (Stat)3 and enhancement of Akt and Stat5a/b pathways.

Neilson LM, Zhu J, Xie J, Malabarba MG, Sakamoto K, Wagner KU, Kirken RA, Rui H. Neilson LM, et al. Among authors: kirken ra. Mol Endocrinol. 2007 Sep;21(9):2218-32. doi: 10.1210/me.2007-0173. Epub 2007 Jun 5. Mol Endocrinol. 2007. PMID: 17550976

5

Identification of interleukin-2 receptor-associated tyrosine kinase p116 as novel leukocyte-specific Janus kinase.

Kirken RA, Rui H, Malabarba MG, Farrar WL. Kirken RA, et al. J Biol Chem. 1994 Jul 22;269(29):19136-41. J Biol Chem. 1994. PMID: 7518451 Free article.

6

Prolactin activates Ras via signaling proteins SHC, growth factor receptor bound 2, and son of sevenless.

Erwin RA, Kirken RA, Malabarba MG, Farrar WL, Rui H. Erwin RA, et al. Among authors: kirken ra. Endocrinology. 1995 Aug;136(8):3512-8. doi: 10.1210/endo.136.8.7628388. Endocrinology. 1995. PMID: 7628388

7

Activation of JAK3, but not JAK1, is critical to interleukin-4 (IL4) stimulated proliferation and requires a membrane-proximal region of IL4 receptor alpha.

Malabarba MG, Kirken RA, Rui H, Koettnitz K, Kawamura M, O'Shea JJ, Kalthoff FS, Farrar WL. Malabarba MG, et al. Among authors: kirken ra. J Biol Chem. 1995 Apr 21;270(16):9630-7. doi: 10.1074/jbc.270.16.9630. J Biol Chem. 1995. PMID: 7721895 Free article.

8

Phosphorylation and activation of the Jak-3 Janus kinase in response to interleukin-2.

Johnston JA, Kawamura M, Kirken RA, Chen YQ, Blake TB, Shibuya K, Ortaldo JR, McVicar DW, O'Shea JJ. Johnston JA, et al. Among authors: kirken ra. Nature. 1994 Jul 14;370(6485):151-3. doi: 10.1038/370151a0. Nature. 1994. PMID: 8022485

9

Activation of JAK3, but not JAK1, is critical for IL-2-induced proliferation and STAT5 recruitment by a COOH-terminal region of the IL-2 receptor beta-chain.

Kirken RA, Rui H, Malabarba MG, Howard OM, Kawamura M, O'Shea JJ, Farrar WL. Kirken RA, et al. Cytokine. 1995 Oct;7(7):689-700. doi: 10.1006/cyto.1995.0081. Cytokine. 1995. PMID: 8580378

10

Prolactin recruits STAT1, STAT3 and STAT5 independent of conserved receptor tyrosines TYR402, TYR479, TYR515 and TYR580.

DaSilva L, Rui H, Erwin RA, Howard OM, Kirken RA, Malabarba MG, Hackett RH, Larner AC, Farrar WL. DaSilva L, et al. Among authors: kirken ra. Mol Cell Endocrinol. 1996 Mar 25;117(2):131-40. doi: 10.1016/0303-7207(95)03738-1. Mol Cell Endocrinol. 1996. PMID: 8737372

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