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Synthesis of isomeric 3-piperidinyl and 3-pyrrolidinyl benzo[5,6]cyclohepta[1,2-b]pyridines: sulfonamido derivatives as inhibitors of Ras prenylation.
Bioorg Med Chem. 1998 Jun;6(6):673-86. doi: 10.1016/s0968-0896(98)00026-1.
Bioorg Med Chem. 1998.
PMID: 9681133
Analogues of 1-(3,10-dibromo-8-chloro-6,11-dihydro-5H-benzo-[5,6]-cyclohepta [1,2-b]pyridin-11-yl)piperidine as inhibitors of farnesyl protein transferase.
Afonso A, Weinstein J, Kelly J, Wolin R, Rosenblum SB, Connolly M, Guzi T, James L, Carr D, Patton R, Bishop WR, Kirshmeier P, Liu M, Heimark L, Chen KJ, Nomeir AA.
Afonso A, et al. Among authors: kirshmeier p.
Bioorg Med Chem. 1999 Sep;7(9):1845-55. doi: 10.1016/s0968-0896(99)00103-0.
Bioorg Med Chem. 1999.
PMID: 10530932
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Different structural requirements within the switch II region of the Ras protein for interactions with specific downstream targets.
Moodie SA, Paris M, Villafranca E, Kirshmeier P, Willumsen BM, Wolfman A.
Moodie SA, et al. Among authors: kirshmeier p.
Oncogene. 1995 Aug 3;11(3):447-54.
Oncogene. 1995.
PMID: 7630628
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