Slack R - Search Results

1

Microsatellite instability, chemosensitivity and mutant frequency in a series of 1,2-dimethylhydrazine induced murine colon adenocarcinoma models.

Thompson MJ, Slack R, Double JA, Bibby MC. Thompson MJ, et al. Among authors: slack r. Int J Oncol. 1998 Sep;13(3):531-6. doi: 10.3892/ijo.13.3.531. Int J Oncol. 1998. PMID: 9683789

2

A simple and effective daily pain management method for patients receiving radiation therapy for painful bone metastases.

Andrade RS, Proctor JW, Slack R, Marlowe U, Ashby KR, Schenken LL. Andrade RS, et al. Among authors: slack r. Int J Radiat Oncol Biol Phys. 2010 Nov 1;78(3):855-9. doi: 10.1016/j.ijrobp.2009.09.002. Epub 2010 Feb 19. Int J Radiat Oncol Biol Phys. 2010. PMID: 20171810 Free PMC article.

3

Evaluation of Patient Navigation in a Community Radiation Oncology Center Involved in Disparities Studies: A Time-to-Completion-of-Treatment Study.

Schwaderer KA, Proctor JW, Martz EF, Slack RJ, Ricci E. Schwaderer KA, et al. J Oncol Pract. 2008;4(5):220-224. doi: 10.1200/JOP.0852001. J Oncol Pract. 2008. PMID: 19169417 Free PMC article.

4

Development and Characterization of a High-Affinity Selective Galectin-3 Mouse Tool Compound in Mouse Models of Cancer.

Peterson K, Nilsson UJ, Gravelle L, Holyer I, Jansson K, Kahl-Knutson B, Leffler H, MacKinnon AC, Roper JA, Slack RJ, Wachenfeldt HV, Pedersen A, Zetterberg FR. Peterson K, et al. Among authors: slack rj. J Med Chem. 2024 Dec 26;67(24):21905-21915. doi: 10.1021/acs.jmedchem.4c01747. Epub 2024 Dec 12. J Med Chem. 2024. PMID: 39668131

5

Galectin-1 Induces the Production of Immune-Suppressive Cytokines in Human and Mouse T Cells.

Herman KD, Holyer I, Humphries DC, Adamska A, Roper JA, Peterson K, Zetterberg FR, Pedersen A, MacKinnon AC, Slack RJ. Herman KD, et al. Among authors: slack rj. Int J Mol Sci. 2024 Nov 7;25(22):11948. doi: 10.3390/ijms252211948. Int J Mol Sci. 2024. PMID: 39596018 Free PMC article.

6

Distinct fingerprints of tRNA-derived small non-coding RNA in animal models of neurodegeneration.

Baindoor S, Gibriel HAY, Venø MT, Su J, Morrissey EP, Jirström E, Woods I, Kenny A, Alves M, Halang L, Fabbrizio P, Bilen M, Engel T, Hogg MC, Bendotti C, Nardo G, Slack RS, Kjems J, Prehn JHM. Baindoor S, et al. Among authors: slack rs. Dis Model Mech. 2024 Nov 1;17(11):dmm050870. doi: 10.1242/dmm.050870. Epub 2024 Nov 18. Dis Model Mech. 2024. PMID: 39552337 Free PMC article.

7

Effect of GB1107, a novel galectin-3 inhibitor on pro-fibrotic signalling in the liver.

MacKinnon AC, Humphries DC, Herman K, Roper JA, Holyer I, Mabbitt J, Mills R, Nilsson UJ, Leffler H, Pedersen A, Schambye H, Zetterberg F, Slack RJ. MacKinnon AC, et al. Among authors: slack rj. Eur J Pharmacol. 2024 Dec 15;985:177077. doi: 10.1016/j.ejphar.2024.177077. Epub 2024 Nov 9. Eur J Pharmacol. 2024. PMID: 39528104

8

Core Modifications of GSK3335103 toward Orally Bioavailable α_vβ₆ Inhibitors with Improved Synthetic Tractability.

Hryczanek HF, Barrett J, Barrett TN, Burley GA, Cookson RE, Hatley RJD, Measom ND, Roper JA, Rowedder JE, Slack RJ, Śmieja CB, Macdonald SJF. Hryczanek HF, et al. Among authors: slack rj. J Med Chem. 2024 Nov 14;67(21):19689-19715. doi: 10.1021/acs.jmedchem.4c02051. Epub 2024 Oct 17. J Med Chem. 2024. PMID: 39417301

9

Single‑Dose Pharmacokinetics and Safety of the Oral Galectin‑3 Inhibitor, Selvigaltin (GB1211), in Participants with Hepatic Impairment.

Aslanis V, Gray M, Slack RJ, Zetterberg FR, Tonev D, Phung D, Smith B, Jacoby B, Schambye H, Krastev Z, Ungell AL, Lindmark B. Aslanis V, et al. Among authors: slack rj. Clin Drug Investig. 2024 Oct;44(10):773-787. doi: 10.1007/s40261-024-01395-7. Epub 2024 Oct 2. Clin Drug Investig. 2024. PMID: 39358661 Clinical Trial.

10

Discovery and Development of Highly Potent and Orally Bioavailable Nonpeptidic α_vβ₆ Integrin Inhibitors.

Procopiou PA, Barrett J, Crawford MHJ, Hatley RJD, Hancock AP, Pritchard JM, Rowedder JE, Copley RCB, Slack RJ, Sollis SL, Thorp LR, Lippa RA, Macdonald SJF, Barrett TN. Procopiou PA, et al. Among authors: slack rj. J Med Chem. 2024 Oct 10;67(19):17497-17519. doi: 10.1021/acs.jmedchem.4c01430. Epub 2024 Sep 13. J Med Chem. 2024. PMID: 39269712

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