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Page 1
Indole-2-carboxamide inhibitors of human liver glycogen phosphorylase.
Hoover DJ, Lefkowitz-Snow S, Burgess-Henry JL, Martin WH, Armento SJ, Stock IA, McPherson RK, Genereux PE, Gibbs EM, Treadway JL. Hoover DJ, et al. Among authors: stock ia. J Med Chem. 1998 Jul 30;41(16):2934-8. doi: 10.1021/jm980264k. J Med Chem. 1998. PMID: 9685232 No abstract available.
CP-481,715, a potent and selective CCR1 antagonist with potential therapeutic implications for inflammatory diseases.
Gladue RP, Tylaska LA, Brissette WH, Lira PD, Kath JC, Poss CS, Brown MF, Paradis TJ, Conklyn MJ, Ogborne KT, McGlynn MA, Lillie BM, DiRico AP, Mairs EN, McElroy EB, Martin WH, Stock IA, Shepard RM, Showell HJ, Neote K. Gladue RP, et al. Among authors: stock ia. J Biol Chem. 2003 Oct 17;278(42):40473-80. doi: 10.1074/jbc.M306875200. Epub 2003 Aug 7. J Biol Chem. 2003. PMID: 12909630 Free article.
Benzimidazolone p38 inhibitors.
Dombroski MA, Letavic MA, McClure KF, Barberia JT, Carty TJ, Cortina SR, Csiki C, Dipesa AJ, Elliott NC, Gabel CA, Jordan CK, Labasi JM, Martin WH, Peese KM, Stock IA, Svensson L, Sweeney FJ, Yu CH. Dombroski MA, et al. Among authors: stock ia. Bioorg Med Chem Lett. 2004 Feb 23;14(4):919-23. doi: 10.1016/j.bmcl.2003.12.023. Bioorg Med Chem Lett. 2004. PMID: 15012994
Potent small molecule CCR1 antagonists.
Kath JC, Brissette WH, Brown MF, Conklyn M, DiRico AP, Dorff P, Gladue RP, Lillie BM, Lira PD, Mairs EN, Martin WH, McElroy EB, McGlynn MA, Paradis TJ, Poss CS, Stock IA, Tylaska LA, Zheng D. Kath JC, et al. Among authors: stock ia. Bioorg Med Chem Lett. 2004 May 3;14(9):2169-73. doi: 10.1016/j.bmcl.2004.02.021. Bioorg Med Chem Lett. 2004. PMID: 15081002
Discovery of PF-06835919: A Potent Inhibitor of Ketohexokinase (KHK) for the Treatment of Metabolic Disorders Driven by the Overconsumption of Fructose.
Futatsugi K, Smith AC, Tu M, Raymer B, Ahn K, Coffey SB, Dowling MS, Fernando DP, Gutierrez JA, Huard K, Jasti J, Kalgutkar AS, Knafels JD, Pandit J, Parris KD, Perez S, Pfefferkorn JA, Price DA, Ryder T, Shavnya A, Stock IA, Tsai AS, Tesz GJ, Thuma BA, Weng Y, Wisniewska HM, Xing G, Zhou J, Magee TV. Futatsugi K, et al. Among authors: stock ia. J Med Chem. 2020 Nov 25;63(22):13546-13560. doi: 10.1021/acs.jmedchem.0c00944. Epub 2020 Sep 27. J Med Chem. 2020. PMID: 32910646
Identification of spirocyclic piperidine-azetidine inverse agonists of the ghrelin receptor.
Kung DW, Coffey SB, Jones RM, Cabral S, Jiao W, Fichtner M, Carpino PA, Rose CR, Hank RF, Lopaze MG, Swartz R, Chen HT, Hendsch Z, Posner B, Wielis CF, Manning B, Dubins J, Stock IA, Varma S, Campbell M, DeBartola D, Kosa-Maines R, Steyn SJ, McClure KF. Kung DW, et al. Among authors: stock ia. Bioorg Med Chem Lett. 2012 Jul 1;22(13):4281-7. doi: 10.1016/j.bmcl.2012.05.024. Epub 2012 May 17. Bioorg Med Chem Lett. 2012. PMID: 22677316
Identification of potent, selective, CNS-targeted inverse agonists of the ghrelin receptor.
McClure KF, Jackson M, Cameron KO, Kung DW, Perry DA, Orr ST, Zhang Y, Kohrt J, Tu M, Gao H, Fernando D, Jones R, Erasga N, Wang G, Polivkova J, Jiao W, Swartz R, Ueno H, Bhattacharya SK, Stock IA, Varma S, Bagdasarian V, Perez S, Kelly-Sullivan D, Wang R, Kong J, Cornelius P, Michael L, Lee E, Janssen A, Steyn SJ, Lapham K, Goosen T. McClure KF, et al. Among authors: stock ia. Bioorg Med Chem Lett. 2013 Oct 1;23(19):5410-4. doi: 10.1016/j.bmcl.2013.07.044. Epub 2013 Jul 30. Bioorg Med Chem Lett. 2013. PMID: 23953189
21 results