Wyatt JR - Search Results

1

Inhibition of human immunodeficiency virus type 1 infection in SCID-hu Thy/Liv mice by the G-quartet-forming oligonucleotide, ISIS 5320.

Stoddart CA, Rabin L, Hincenbergs M, Moreno M, Linquist-Stepps V, Leeds JM, Truong LA, Wyatt JR, Ecker DJ, McCune JM. Stoddart CA, et al. Among authors: wyatt jr. Antimicrob Agents Chemother. 1998 Aug;42(8):2113-5. doi: 10.1128/AAC.42.8.2113. Antimicrob Agents Chemother. 1998. PMID: 9687417 Free PMC article.

2

Potent and specific inhibition of HIV envelope-mediated cell fusion and virus binding by G quartet-forming oligonucleotide (ISIS 5320).

Buckheit RW Jr, Roberson JL, Lackman-Smith C, Wyatt JR, Vickers TA, Ecker DJ. Buckheit RW Jr, et al. Among authors: wyatt jr. AIDS Res Hum Retroviruses. 1994 Nov;10(11):1497-506. doi: 10.1089/aid.1994.10.1497. AIDS Res Hum Retroviruses. 1994. PMID: 7888204

3

Combinatorially selected guanosine-quartet structure is a potent inhibitor of human immunodeficiency virus envelope-mediated cell fusion.

Wyatt JR, Vickers TA, Roberson JL, Buckheit RW Jr, Klimkait T, DeBaets E, Davis PW, Rayner B, Imbach JL, Ecker DJ. Wyatt JR, et al. Proc Natl Acad Sci U S A. 1994 Feb 15;91(4):1356-60. doi: 10.1073/pnas.91.4.1356. Proc Natl Acad Sci U S A. 1994. PMID: 7906414 Free PMC article.

4

Strategies for rapid deconvolution of combinational libraries: comparative evaluation using a model system.

Konings DA, Wyatt JR, Ecker DJ, Freier SM. Konings DA, et al. Among authors: wyatt jr. J Med Chem. 1997 Dec 19;40(26):4386-95. doi: 10.1021/jm970503o. J Med Chem. 1997. PMID: 9435908

5

Deconvolution of combinatorial libraries for drug discovery: a model system.

Freier SM, Konings DA, Wyatt JR, Ecker DJ. Freier SM, et al. Among authors: wyatt jr. J Med Chem. 1995 Jan 20;38(2):344-52. doi: 10.1021/jm00002a016. J Med Chem. 1995. PMID: 7830277

6

Deconvolution of combinatorial libraries for Drug discovery: theoretical comparison of pooling strategies.

Konings DA, Wyatt JR, Ecker DJ, Freier SM. Konings DA, et al. Among authors: wyatt jr. J Med Chem. 1996 Jul 5;39(14):2710-9. doi: 10.1021/jm960168o. J Med Chem. 1996. PMID: 8709101

7

Structure-activity relationships of novel 2-substituted quinazoline antibacterial agents.

Kung PP, Casper MD, Cook KL, Wilson-Lingardo L, Risen LM, Vickers TA, Ranken R, Blyn LB, Wyatt JR, Cook PD, Ecker DJ. Kung PP, et al. Among authors: wyatt jr. J Med Chem. 1999 Nov 4;42(22):4705-13. doi: 10.1021/jm9903500. J Med Chem. 1999. PMID: 10579832

8

Drug leads from combinatorial phosphodiester libraries.

Davis PW, Vickers TA, Wilson-Lingardo L, Wyatt JR, Guinosso CJ, Sanghvi YS, DeBaets EA, Acevedo OL, Cook PD, Ecker DJ. Davis PW, et al. Among authors: wyatt jr. J Med Chem. 1995 Oct 27;38(22):4363-6. doi: 10.1021/jm00022a002. J Med Chem. 1995. PMID: 7473564 No abstract available.

9

Deconvolution of combinatorial libraries for drug discovery: experimental comparison of pooling strategies.

Wilson-Lingardo L, Davis PW, Ecker DJ, Hébert N, Acevedo O, Sprankle K, Brennan T, Schwarcz L, Freier SM, Wyatt JR. Wilson-Lingardo L, et al. Among authors: wyatt jr. J Med Chem. 1996 Jul 5;39(14):2720-6. doi: 10.1021/jm960169g. J Med Chem. 1996. PMID: 8709102

10

'Mutational SURF': a strategy for improving lead compounds identified from combinatorial libraries.

Freier SM, Konings DA, Wyatt JR, Ecker DJ. Freier SM, et al. Among authors: wyatt jr. Bioorg Med Chem. 1996 May;4(5):717-25. doi: 10.1016/0968-0896(96)00068-5. Bioorg Med Chem. 1996. PMID: 8804538

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