Koepsell H - Search Results

1

Human neurons express the polyspecific cation transporter hOCT2, which translocates monoamine neurotransmitters, amantadine, and memantine.

Busch AE, Karbach U, Miska D, Gorboulev V, Akhoundova A, Volk C, Arndt P, Ulzheimer JC, Sonders MS, Baumann C, Waldegger S, Lang F, Koepsell H. Busch AE, et al. Among authors: koepsell h. Mol Pharmacol. 1998 Aug;54(2):342-52. doi: 10.1124/mol.54.2.342. Mol Pharmacol. 1998. PMID: 9687576

2

Different affinities of inhibitors to the outwardly and inwardly directed substrate binding site of organic cation transporter 2.

Volk C, Gorboulev V, Budiman T, Nagel G, Koepsell H. Volk C, et al. Among authors: koepsell h. Mol Pharmacol. 2003 Nov;64(5):1037-47. doi: 10.1124/mol.64.5.1037. Mol Pharmacol. 2003. PMID: 14573752

3

Subtype-specific affinity for corticosterone of rat organic cation transporters rOCT1 and rOCT2 depends on three amino acids within the substrate binding region.

Gorboulev V, Shatskaya N, Volk C, Koepsell H. Gorboulev V, et al. Among authors: koepsell h. Mol Pharmacol. 2005 May;67(5):1612-9. doi: 10.1124/mol.104.008821. Epub 2005 Jan 20. Mol Pharmacol. 2005. PMID: 15662045

4

Electrogenic properties and substrate specificity of the polyspecific rat cation transporter rOCT1.

Busch AE, Quester S, Ulzheimer JC, Waldegger S, Gorboulev V, Arndt P, Lang F, Koepsell H. Busch AE, et al. Among authors: koepsell h. J Biol Chem. 1996 Dec 20;271(51):32599-604. doi: 10.1074/jbc.271.51.32599. J Biol Chem. 1996. PMID: 8955087 Free article.

The previously cloned rat cation transporter rOCT1 detected in renal proximal tubules and hepatocytes (Grundemann, D., Gorboulev, V., Gambaryan, S., Veyhl, M., and Koepsell, H. (1994) Nature 372, 549-552) was expressed in Xenopus oocytes, and transport properties we …

The previously cloned rat cation transporter rOCT1 detected in renal proximal tubules and hepatocytes (Grundemann, D., Gorboulev, V., Gambar …

5

Cloning and characterization of two human polyspecific organic cation transporters.

Gorboulev V, Ulzheimer JC, Akhoundova A, Ulzheimer-Teuber I, Karbach U, Quester S, Baumann C, Lang F, Busch AE, Koepsell H. Gorboulev V, et al. Among authors: koepsell h. DNA Cell Biol. 1997 Jul;16(7):871-81. doi: 10.1089/dna.1997.16.871. DNA Cell Biol. 1997. PMID: 9260930

6

A reevaluation of substrate specificity of the rat cation transporter rOCT1.

Nagel G, Volk C, Friedrich T, Ulzheimer JC, Bamberg E, Koepsell H. Nagel G, et al. Among authors: koepsell h. J Biol Chem. 1997 Dec 19;272(51):31953-6. doi: 10.1074/jbc.272.51.31953. J Biol Chem. 1997. PMID: 9405386 Free article.

C., Waldegger, S., Gorboulev, V., Arndt, P., Lang, F., and Koepsell, H. (1996) J. Biol. Chem. 271, 32599-32604). Tracer flux measurements with oocytes and with stably transfected human embryonic kidney cells showed that [3H]quinine and [3H]quinidine are not transpor …

C., Waldegger, S., Gorboulev, V., Arndt, P., Lang, F., and Koepsell, H. (1996) J. Biol. Chem. 271, 32599-32604). Tracer flux m …

7

Selectivity of the polyspecific cation transporter rOCT1 is changed by mutation of aspartate 475 to glutamate.

Gorboulev V, Volk C, Arndt P, Akhoundova A, Koepsell H. Gorboulev V, et al. Among authors: koepsell h. Mol Pharmacol. 1999 Dec;56(6):1254-61. doi: 10.1124/mol.56.6.1254. Mol Pharmacol. 1999. PMID: 10570053

8

Monoamine neurotransmitter transport mediated by the polyspecific cation transporter rOCT1.

Busch AE, Quester S, Ulzheimer JC, Gorboulev V, Akhoundova A, Waldegger S, Lang F, Koepsell H. Busch AE, et al. Among authors: koepsell h. FEBS Lett. 1996 Oct 21;395(2-3):153-6. doi: 10.1016/0014-5793(96)01030-7. FEBS Lett. 1996. PMID: 8898084 Free article.

9

Membrane localization of the electrogenic cation transporter rOCT1 in rat liver.

Meyer-Wentrup F, Karbach U, Gorboulev V, Arndt P, Koepsell H. Meyer-Wentrup F, et al. Among authors: koepsell h. Biochem Biophys Res Commun. 1998 Jul 30;248(3):673-8. doi: 10.1006/bbrc.1998.9034. Biochem Biophys Res Commun. 1998. PMID: 9703985

10

The cation transporters rOCT1 and rOCT2 interact with bicarbonate but play only a minor role for amantadine uptake into rat renal proximal tubules.

Goralski KB, Lou G, Prowse MT, Gorboulev V, Volk C, Koepsell H, Sitar DS. Goralski KB, et al. Among authors: koepsell h. J Pharmacol Exp Ther. 2002 Dec;303(3):959-68. doi: 10.1124/jpet.102.038885. J Pharmacol Exp Ther. 2002. PMID: 12438515

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