Staunton J - Search Results

1

Engineering of a minimal modular polyketide synthase, and targeted alteration of the stereospecificity of polyketide chain extension.

Böhm I, Holzbaur IE, Hanefeld U, Cortés J, Staunton J, Leadlay PF. Böhm I, et al. Among authors: staunton j. Chem Biol. 1998 Aug;5(8):407-12. doi: 10.1016/s1074-5521(98)90157-0. Chem Biol. 1998. PMID: 9710562

2

A new modular polyketide synthase in the erythromycin producer Saccharopolyspora erythraea.

Boakes S, Oliynyk M, Cortés J, Böhm I, Rudd BA, Revill WP, Staunton J, Leadlay PF. Boakes S, et al. Among authors: staunton j. J Mol Microbiol Biotechnol. 2004;8(2):73-80. doi: 10.1159/000084562. J Mol Microbiol Biotechnol. 2004. PMID: 15925898

3

Stereochemistry of catalysis by the ketoreductase activity in the first extension module of the erythromycin polyketide synthase.

Østergaard LH, Kellenberger L, Cortés J, Roddis MP, Deacon M, Staunton J, Leadlay PF. Østergaard LH, et al. Among authors: staunton j. Biochemistry. 2002 Feb 26;41(8):2719-26. doi: 10.1021/bi0117605. Biochemistry. 2002. PMID: 11851419

4

Engineering specificity of starter unit selection by the erythromycin-producing polyketide synthase.

Long PF, Wilkinson CJ, Bisang CP, Cortés J, Dunster N, Oliynyk M, McCormick E, McArthur H, Mendez C, Salas JA, Staunton J, Leadlay PF. Long PF, et al. Among authors: staunton j. Mol Microbiol. 2002 Mar;43(5):1215-25. doi: 10.1046/j.1365-2958.2002.02815.x. Mol Microbiol. 2002. PMID: 11918808 Free article.

5

Skipping in a hybrid polyketide synthase. Evidence for ACP-to-ACP chain transfer.

Thomas I, Martin CJ, Wilkinson CJ, Staunton J, Leadlay PF. Thomas I, et al. Among authors: staunton j. Chem Biol. 2002 Jul;9(7):781-7. doi: 10.1016/s1074-5521(02)00164-3. Chem Biol. 2002. PMID: 12144921

6

Molecular basis of Celmer's rules: stereochemistry of catalysis by isolated ketoreductase domains from modular polyketide synthases.

Siskos AP, Baerga-Ortiz A, Bali S, Stein V, Mamdani H, Spiteller D, Popovic B, Spencer JB, Staunton J, Weissman KJ, Leadlay PF. Siskos AP, et al. Among authors: staunton j. Chem Biol. 2005 Oct;12(10):1145-53. doi: 10.1016/j.chembiol.2005.08.017. Chem Biol. 2005. PMID: 16242657

7

A polylinker approach to reductive loop swaps in modular polyketide synthases.

Kellenberger L, Galloway IS, Sauter G, Böhm G, Hanefeld U, Cortés J, Staunton J, Leadlay PF. Kellenberger L, et al. Among authors: staunton j. Chembiochem. 2008 Nov 3;9(16):2740-9. doi: 10.1002/cbic.200800332. Chembiochem. 2008. PMID: 18937219

8

Identification of DEBS 1, DEBS 2 and DEBS 3, the multienzyme polypeptides of the erythromycin-producing polyketide synthase from Saccharopolyspora erythraea.

Caffrey P, Bevitt DJ, Staunton J, Leadlay PF. Caffrey P, et al. Among authors: staunton j. FEBS Lett. 1992 Jun 15;304(2-3):225-8. doi: 10.1016/0014-5793(92)80624-p. FEBS Lett. 1992. PMID: 1618327 Free article.

9

Repositioning of a domain in a modular polyketide synthase to promote specific chain cleavage.

Cortes J, Wiesmann KE, Roberts GA, Brown MJ, Staunton J, Leadlay PF. Cortes J, et al. Among authors: staunton j. Science. 1995 Jun 9;268(5216):1487-9. doi: 10.1126/science.7770773. Science. 1995. PMID: 7770773

10

Limited proteolysis and active-site studies of the first multienzyme component of the erythromycin-producing polyketide synthase.

Aparicio JF, Caffrey P, Marsden AF, Staunton J, Leadlay PF. Aparicio JF, et al. Among authors: staunton j. J Biol Chem. 1994 Mar 18;269(11):8524-8. J Biol Chem. 1994. PMID: 8132579 Free article.

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