Gros P - Search Results

1

High-level expression of mouse Mdr3 P-glycoprotein in yeast Pichia pastoris and characterization of ATPase activity.

Beaudet L, Urbatsch IL, Gros P. Beaudet L, et al. Among authors: gros p. Methods Enzymol. 1998;292:397-413. doi: 10.1016/s0076-6879(98)92031-6. Methods Enzymol. 1998. PMID: 9711570 No abstract available.

2

A single amino acid substitution strongly modulates the activity and substrate specificity of the mouse mdr1 and mdr3 drug efflux pumps.

Gros P, Dhir R, Croop J, Talbot F. Gros P, et al. Proc Natl Acad Sci U S A. 1991 Aug 15;88(16):7289-93. doi: 10.1073/pnas.88.16.7289. Proc Natl Acad Sci U S A. 1991. PMID: 1678520 Free PMC article.

3

Membrane topology of P-glycoprotein as determined by epitope insertion: transmembrane organization of the N-terminal domain of mdr3.

Kast C, Canfield V, Levenson R, Gros P. Kast C, et al. Among authors: gros p. Biochemistry. 1995 Apr 4;34(13):4402-11. doi: 10.1021/bi00013a032. Biochemistry. 1995. PMID: 7535563

4

P-glycoprotein homologues.

Buschman E, Lepage P, Gros P. Buschman E, et al. Among authors: gros p. Cancer Treat Res. 1994;73:17-39. doi: 10.1007/978-1-4615-2632-2_2. Cancer Treat Res. 1994. PMID: 7536017 Review. No abstract available.

5

Functional dissection of P-glycoprotein nucleotide-binding domains in chimeric and mutant proteins. Modulation of drug resistance profiles.

Beaudet L, Gros P. Beaudet L, et al. Among authors: gros p. J Biol Chem. 1995 Jul 21;270(29):17159-70. doi: 10.1074/jbc.270.29.17159. J Biol Chem. 1995. PMID: 7615512 Free article.

6

Human (MDR1) and mouse (mdr1, mdr3) P-glycoproteins can be distinguished by their respective drug resistance profiles and sensitivity to modulators.

Tang-Wai DF, Kajiji S, DiCapua F, de Graaf D, Roninson IB, Gros P. Tang-Wai DF, et al. Among authors: gros p. Biochemistry. 1995 Jan 10;34(1):32-9. doi: 10.1021/bi00001a005. Biochemistry. 1995. PMID: 7819214

7

Functional expression of P-glycoprotein encoded by the mouse mdr3 gene in yeast cells.

Ruetz S, Raymond M, Gros P. Ruetz S, et al. Among authors: gros p. Proc Natl Acad Sci U S A. 1993 Dec 15;90(24):11588-92. doi: 10.1073/pnas.90.24.11588. Proc Natl Acad Sci U S A. 1993. PMID: 7903452 Free PMC article.

8

A mechanism for P-glycoprotein action in multidrug resistance: are we there yet?

Ruetz S, Gros P. Ruetz S, et al. Among authors: gros p. Trends Pharmacol Sci. 1994 Jul;15(7):260-3. doi: 10.1016/0165-6147(94)90322-0. Trends Pharmacol Sci. 1994. PMID: 7940990 Review.

Multidrug resistance is associated with the overexpression of P-glycoprotein, a membrane glycoprotein. The mechanism by which P-glycoprotein confers to cells the capacity to resist cytotoxic attack by structurally unrelated drugs has remained difficult to decipher. …

Multidrug resistance is associated with the overexpression of P-glycoprotein, a membrane glycoprotein. The mechanism by which P …

9

Functional expression of the multidrug resistance-associated protein in the yeast Saccharomyces cerevisiae.

Ruetz S, Brault M, Kast C, Hemenway C, Heitman J, Grant CE, Cole SP, Deeley RG, Gros P. Ruetz S, et al. Among authors: gros p. J Biol Chem. 1996 Feb 23;271(8):4154-60. doi: 10.1074/jbc.271.8.4154. J Biol Chem. 1996. Retraction in: J Biol Chem. 1999 Jan 22;274(4):2592. PMID: 8626756 Free article. Retracted.

10

Mutations in either nucleotide-binding site of P-glycoprotein (Mdr3) prevent vanadate trapping of nucleotide at both sites.

Urbatsch IL, Beaudet L, Carrier I, Gros P. Urbatsch IL, et al. Among authors: gros p. Biochemistry. 1998 Mar 31;37(13):4592-602. doi: 10.1021/bi9728001. Biochemistry. 1998. PMID: 9521779

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