Hopkins NE - Search Results

1

Selectivity of polycyclic inhibitors for human cytochrome P450s 1A1, 1A2, and 1B1.

Shimada T, Yamazaki H, Foroozesh M, Hopkins NE, Alworth WL, Guengerich FP. Shimada T, et al. Among authors: hopkins ne. Chem Res Toxicol. 1998 Sep;11(9):1048-56. doi: 10.1021/tx980090+. Chem Res Toxicol. 1998. PMID: 9760279

2

Interaction of polycyclic aromatic hydrocarbons with human cytochrome P450 1B1 in inhibiting catalytic activity.

Shimada T, Murajama N, Tanaka K, Takenaka S, Imai Y, Hopkins NE, Foroozesh MK, Alworth WL, Yamazaki H, Guengerich FP, Komori M. Shimada T, et al. Among authors: hopkins ne. Chem Res Toxicol. 2008 Dec;21(12):2313-23. doi: 10.1021/tx8002998. Chem Res Toxicol. 2008. PMID: 19548353 Free PMC article.

3

Modification of cytochrome P450 1A2 enzymes by the mechanism-based inactivator 2-ethynylnaphthalene and the photoaffinity label 4-azidobiphenyl.

Yun CH, Hammons GJ, Jones G, Martin MV, Hopkins NE, Alworth WL, Guengerich FP. Yun CH, et al. Among authors: hopkins ne. Biochemistry. 1992 Nov 3;31(43):10556-63. doi: 10.1021/bi00158a019. Biochemistry. 1992. PMID: 1420171

4

2-ethynylnaphthalene as a mechanism-based inactivator of the cytochrome P-450 catalyzed N-oxidation of 2-naphthylamine.

Hammons GJ, Alworth WL, Hopkins NE, Guengerich FP, Kadlubar FF. Hammons GJ, et al. Among authors: hopkins ne. Chem Res Toxicol. 1989 Nov-Dec;2(6):367-74. doi: 10.1021/tx00012a003. Chem Res Toxicol. 1989. PMID: 2519725

5

Suicide inhibitors of cytochrome P450 1A1 and P450 2B1.

Hopkins NE, Foroozesh MK, Alworth WL. Hopkins NE, et al. Biochem Pharmacol. 1992 Aug 18;44(4):787-96. doi: 10.1016/0006-2952(92)90417-h. Biochem Pharmacol. 1992. PMID: 1510726

6

Mechanism-based inactivation of cytochrome P450 2B1 by 2-ethynylnaphthalene: identification of an active-site peptide.

Roberts ES, Hopkins NE, Alworth WL, Hollenberg PF. Roberts ES, et al. Among authors: hopkins ne. Chem Res Toxicol. 1993 Jul-Aug;6(4):470-9. doi: 10.1021/tx00034a013. Chem Res Toxicol. 1993. PMID: 8374044

7

Effects of 1-ethynylpyrene and related inhibitors of P450 isozymes upon benzo[a]pyrene metabolism by liver microsomes.

Hall M, Parker DK, Grover PL, Lu JY, Hopkins NE, Alworth WL. Hall M, et al. Among authors: hopkins ne. Chem Biol Interact. 1990;76(2):181-92. doi: 10.1016/0009-2797(90)90087-4. Chem Biol Interact. 1990. PMID: 2225228

8

Inactivation of cytochrome P450s 2B1, 2B4, 2B6, and 2B11 by arylalkynes.

Roberts ES, Hopkins NE, Foroozesh M, Alworth WL, Halpert JR, Hollenberg PF. Roberts ES, et al. Among authors: hopkins ne. Drug Metab Dispos. 1997 Nov;25(11):1242-8. Drug Metab Dispos. 1997. PMID: 9351899 Clinical Trial.

9

Catalytic properties of an expressed cytochrome P450 2B1 from a Wistar-Kyoto rat liver cDNA library.

Kobayashi Y, Strobel SM, Hopkins NE, Alworth WL, Halpert JR. Kobayashi Y, et al. Among authors: hopkins ne. Drug Metab Dispos. 1998 Oct;26(10):1026-30. Drug Metab Dispos. 1998. PMID: 9763409

10

Mechanistic studies of 9-ethynylphenanthrene-inactivated cytochrome P450 2B1.

Roberts ES, Ballou DP, Hopkins NE, Alworth WL, Hollenberg PF. Roberts ES, et al. Among authors: hopkins ne. Arch Biochem Biophys. 1995 Nov 10;323(2):303-12. doi: 10.1006/abbi.1995.9960. Arch Biochem Biophys. 1995. PMID: 7487092

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