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Knock out of alpha1,3-galactosyltransferase or expression of alpha1,2-fucosyltransferase further protects CD55- and CD59-expressing mouse hearts in an ex vivo model of xenograft rejection.
Cowan PJ, Chen CG, Shinkel TA, Fisicaro N, Salvaris E, Aminian A, Romanella M, Pearse MJ, d'Apice AJ. Cowan PJ, et al. Among authors: romanella m. Transplantation. 1998 Jun 27;65(12):1599-604. doi: 10.1097/00007890-199806270-00010. Transplantation. 1998. PMID: 9665076
High-level co-expression of complement regulators on vascular endothelium in transgenic mice: CD55 and CD59 provide greater protection from human complement-mediated injury than CD59 alone.
Cowan PJ, Shinkel TA, Aminian A, Romanella M, Wigley PL, Lonie AJ, Nottle MB, Pearse MJ, d'Apice AJ. Cowan PJ, et al. Among authors: romanella m. Xenotransplantation. 1998 Aug;5(3):184-90. doi: 10.1111/j.1399-3089.1998.tb00026.x. Xenotransplantation. 1998. PMID: 9741456
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