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Internal sphincterotomy is superior to topical nitroglycerin in the treatment of chronic anal fissure: results of a randomized, controlled trial by the Canadian Colorectal Surgical Trials Group.
Richard CS, Gregoire R, Plewes EA, Silverman R, Burul C, Buie D, Reznick R, Ross T, Burnstein M, O'Connor BI, Mukraj D, McLeod RS. Richard CS, et al. Among authors: plewes ea. Dis Colon Rectum. 2000 Aug;43(8):1048-57; discussion 1057-8. doi: 10.1007/BF02236548. Dis Colon Rectum. 2000. PMID: 10950002 Clinical Trial.