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APMAT analysis reveals the association between CD8 T cell receptors, cognate antigen, and T cell phenotype and persistence.
Xie J, Chen DG, Chour W, Ng RH, Zhang R, Yuan D, Choi J, McKasson M, Troisch P, Smith B, Jones L, Webster A, Rasheed Y, Li S, Edmark R, Hong S, Murray KM, Logue JK, Franko NM, Lausted CG, Piening B, Algren H, Wallick J, Magis AT, Watanabe K, Mease P, Greenberg PD, Chu H, Goldman JD, Su Y, Heath JR. Xie J, et al. Among authors: greenberg pd. bioRxiv [Preprint]. 2025 Jan 9:2025.01.08.631993. doi: 10.1101/2025.01.08.631993. bioRxiv. 2025. PMID: 39829843 Free PMC article. Preprint.
Acute Myeloid Leukemia Skews Therapeutic WT1-specific CD8 TCR-T Cells Towards an NK-like Phenotype that Compromises Function and Persistence.
Mazziotta F, Martin LE, Eagan DN, Bar M, Kinsella S, Paulson KG, Voillet V, Lahman MC, Hunter D, Schmitt TM, Duerkopp N, Yeung C, Tang TH, Gottardo R, Asano Y, Wilcox EC, Lee B, Zhang T, Lopedote P, Penter L, Wu CJ, Milano F, Greenberg PD, Chapuis AG. Mazziotta F, et al. Among authors: greenberg pd. medRxiv [Preprint]. 2024 Dec 16:2024.12.13.24318504. doi: 10.1101/2024.12.13.24318504. medRxiv. 2024. PMID: 39763516 Free PMC article. Preprint.
Antigen-Specific T Cell Receptor Discovery for Treating Progressive Multifocal Leukoencephalopathy.
Gupta S, Martinov T, Thelen A, Sunahara M, Mureli S, Vazquez A, Gerdts J, Dandekar R, Cortese I, Fouassier C, Schanzer E, Urnov FD, Marson A, Shy BR, Greenberg PD, Wilson MR. Gupta S, et al. Among authors: greenberg pd. bioRxiv [Preprint]. 2024 Nov 4:2024.11.04.621904. doi: 10.1101/2024.11.04.621904. bioRxiv. 2024. PMID: 39574748 Free PMC article. Preprint.
Overcoming immune evasion from post-translational modification of a mutant KRAS epitope to achieve TCR-T cell-mediated antitumor activity.
Lee JW, Chen EY, Hu T, Perret R, Chaffee ME, Martinov T, Mureli S, McCurdy CL, Jones LA, Gafken PR, Chanana P, Su Y, Chapuis AG, Bradley P, Schmitt TM, Greenberg PD. Lee JW, et al. Among authors: greenberg pd. bioRxiv [Preprint]. 2024 Oct 14:2024.09.18.612965. doi: 10.1101/2024.09.18.612965. bioRxiv. 2024. PMID: 39345486 Free PMC article. Preprint.
Tumor Regression Following Engineered Polyomavirus-Specific T Cell Therapy in Immune Checkpoint Inhibitor-Refractory Merkel Cell Carcinoma.
Asano Y, Veatch J, McAfee M, Bakhtiari J, Lee B, Martin L, Zhang S, Mazziotta F, Paulson KG, Schmitt TM, Munkbhat A, Young C, Seaton B, Hunter D, Horst N, Lindberg M, Miller N, Stone M, Bielas J, Koelle D, Voillet V, Gottardo R, Gooley T, Oda S, Greenberg PD, Nghiem P, Chapuis AG. Asano Y, et al. Among authors: greenberg pd. medRxiv [Preprint]. 2024 Jul 5:2024.07.01.24309780. doi: 10.1101/2024.07.01.24309780. medRxiv. 2024. PMID: 39006423 Free PMC article. Preprint.
288 results