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Inhibitor-2 prevents protein phosphatase 1-induced cardiac hypertrophy and mortality.
Brüchert N, Mavila N, Boknik P, Baba HA, Fabritz L, Gergs U, Kirchhefer U, Kirchhof P, Matus M, Schmitz W, DePaoli-Roach AA, Neumann J. Brüchert N, et al. Am J Physiol Heart Circ Physiol. 2008 Oct;295(4):H1539-46. doi: 10.1152/ajpheart.00515.2008. Epub 2008 Aug 8. Am J Physiol Heart Circ Physiol. 2008. PMID: 18689497 Free PMC article.
Type 1 phosphatase, a negative regulator of cardiac function.
Carr AN, Schmidt AG, Suzuki Y, del Monte F, Sato Y, Lanner C, Breeden K, Jing SL, Allen PB, Greengard P, Yatani A, Hoit BD, Grupp IL, Hajjar RJ, DePaoli-Roach AA, Kranias EG. Carr AN, et al. Mol Cell Biol. 2002 Jun;22(12):4124-35. doi: 10.1128/MCB.22.12.4124-4135.2002. Mol Cell Biol. 2002. PMID: 12024026 Free PMC article.
PKC-alpha regulates cardiac contractility and propensity toward heart failure.
Braz JC, Gregory K, Pathak A, Zhao W, Sahin B, Klevitsky R, Kimball TF, Lorenz JN, Nairn AC, Liggett SB, Bodi I, Wang S, Schwartz A, Lakatta EG, DePaoli-Roach AA, Robbins J, Hewett TE, Bibb JA, Westfall MV, Kranias EG, Molkentin JD. Braz JC, et al. Nat Med. 2004 Mar;10(3):248-54. doi: 10.1038/nm1000. Epub 2004 Feb 15. Nat Med. 2004. PMID: 14966518 Free article.
Enhancement of cardiac function and suppression of heart failure progression by inhibition of protein phosphatase 1.
Pathak A, del Monte F, Zhao W, Schultz JE, Lorenz JN, Bodi I, Weiser D, Hahn H, Carr AN, Syed F, Mavila N, Jha L, Qian J, Marreez Y, Chen G, McGraw DW, Heist EK, Guerrero JL, DePaoli-Roach AA, Hajjar RJ, Kranias EG. Pathak A, et al. Circ Res. 2005 Apr 15;96(7):756-66. doi: 10.1161/01.RES.0000161256.85833.fa. Epub 2005 Mar 3. Circ Res. 2005. PMID: 15746443
134 results