Aramori I - Search Results

1

A novel class of orally active non-peptide bradykinin B2 receptor antagonists. 4. Discovery of novel frameworks mimicking the active conformation.

Abe Y, Kayakiri H, Satoh S, Inoue T, Sawada Y, Inamura N, Asano M, Aramori I, Hatori C, Sawai H, Oku T, Tanaka H. Abe Y, et al. Among authors: aramori i. J Med Chem. 1998 Nov 5;41(23):4587-98. doi: 10.1021/jm980330i. J Med Chem. 1998. PMID: 9804698

2

A new series of highly potent non-peptide bradykinin B2 receptor antagonists incorporating the 4-heteroarylquinoline framework. Improvement of aqueous solubility and new insights into species difference.

Sawada Y, Kayakiri H, Abe Y, Imai K, Mizutani T, Inamura N, Asano M, Aramori I, Hatori C, Katayama A, Oku T, Tanaka H. Sawada Y, et al. Among authors: aramori i. J Med Chem. 2004 Mar 25;47(7):1617-30. doi: 10.1021/jm030159x. J Med Chem. 2004. PMID: 15027853

3

A new class of nonpeptide bradykinin B(2) receptor ligand, incorporating a 4-aminoquinoline framework. Identification of a key pharmacophore to determine species difference and agonist/antagonist profile.

Sawada Y, Kayakiri H, Abe Y, Mizutani T, Inamura N, Asano M, Aramori I, Hatori C, Oku T, Tanaka H. Sawada Y, et al. Among authors: aramori i. J Med Chem. 2004 May 6;47(10):2667-77. doi: 10.1021/jm030326t. J Med Chem. 2004. PMID: 15115408

4

Discovery of the first non-peptide full agonists for the human bradykinin B(2) receptor incorporating 4-(2-picolyloxy)quinoline and 1-(2-picolyl)benzimidazole frameworks.

Sawada Y, Kayakiri H, Abe Y, Mizutani T, Inamura N, Asano M, Hatori C, Aramori I, Oku T, Tanaka H. Sawada Y, et al. Among authors: aramori i. J Med Chem. 2004 May 20;47(11):2853-63. doi: 10.1021/jm030468n. J Med Chem. 2004. PMID: 15139763

5

Nonpeptide mimic of bradykinin with long-acting properties at the bradykinin B2 receptor.

Aramori I, Zenkoh J, Morikawa N, Asano M, Hatori C, Sawai H, Kayakiri H, Satoh S, Inoue T, Abe Y, Sawada Y, Mizutani T, Inamura N, Nakahara K, Kojo H, Oku T, Notsu Y. Aramori I, et al. Mol Pharmacol. 1997 Jul;52(1):16-20. doi: 10.1124/mol.52.1.16. Mol Pharmacol. 1997. PMID: 9224807

6

A novel class of orally active non-peptide bradykinin B2 receptor antagonists. 3. Discovering bioisosteres of the imidazo[1,2-a] pyridine moiety.

Abe Y, Kayakiri H, Satoh S, Inoue T, Sawada Y, Inamura N, Asano M, Aramori I, Hatori C, Sawai H, Oku T, Tanaka H. Abe Y, et al. Among authors: aramori i. J Med Chem. 1998 Oct 8;41(21):4062-79. doi: 10.1021/jm980300f. J Med Chem. 1998. PMID: 9767643

7

Nonpeptide mimic of bradykinin with long-acting properties.

Aramori I, Zenkoh J, Morikawa N, Asano M, Hatori C, Sawai H, Kayakiri H, Satoh S, Inoue T, Abe Y, Sawada Y, Mizutani T, Inamura N, Iwami M, Nakahara K, Kojo H, Oku T, Notsu Y. Aramori I, et al. Immunopharmacology. 1999 Dec;45(1-3):185-90. doi: 10.1016/s0162-3109(99)00144-7. Immunopharmacology. 1999. PMID: 10615010

8

Novel subtype-selective nonpeptide bradykinin receptor antagonists FR167344 and FR173657.

Aramori I, Zenkoh J, Morikawa N, O'Donnell N, Asano M, Nakamura K, Iwami M, Kojo H, Notsu Y. Aramori I, et al. Mol Pharmacol. 1997 Feb;51(2):171-6. doi: 10.1124/mol.51.2.171. Mol Pharmacol. 1997. PMID: 9203620

9

Multiple modes of action of tacrolimus (FK506) for neuroprotective action on ischemic damage after transient focal cerebral ischemia in rats.

Furuichi Y, Noto T, Li JY, Oku T, Ishiye M, Moriguchi A, Aramori I, Matsuoka N, Mutoh S, Yanagihara T. Furuichi Y, et al. Among authors: aramori i. Brain Res. 2004 Jul 16;1014(1-2):120-30. doi: 10.1016/j.brainres.2004.04.031. Brain Res. 2004. PMID: 15212998

10

Subtype selectivity of a novel endothelin antagonist, FR139317, for the two endothelin receptors in transfected Chinese hamster ovary cells.

Aramori I, Nirei H, Shoubo M, Sogabe K, Nakamura K, Kojo H, Notsu Y, Ono T, Nakanishi S. Aramori I, et al. Mol Pharmacol. 1993 Feb;43(2):127-31. Mol Pharmacol. 1993. PMID: 8429819

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