Kaushik N - Search Results

1

Phenotypic mechanism of HIV-1 resistance to 3'-azido-3'-deoxythymidine (AZT): increased polymerization processivity and enhanced sensitivity to pyrophosphate of the mutant viral reverse transcriptase.

Arion D, Kaushik N, McCormick S, Borkow G, Parniak MA. Arion D, et al. Among authors: kaushik n. Biochemistry. 1998 Nov 10;37(45):15908-17. doi: 10.1021/bi981200e. Biochemistry. 1998. PMID: 9843396

2

Mutational analysis of Lys65 of HIV-1 reverse transcriptase.

Sluis-Cremer N, Arion D, Kaushik N, Lim H, Parniak MA. Sluis-Cremer N, et al. Among authors: kaushik n. Biochem J. 2000 May 15;348 Pt 1(Pt 1):77-82. Biochem J. 2000. PMID: 10794716 Free PMC article.

3

Role of glutamine-151 of human immunodeficiency virus type-1 reverse transcriptase in RNA-directed DNA synthesis.

Kaushik N, Harris D, Rege N, Modak MJ, Yadav PN, Pandey VN. Kaushik N, et al. Biochemistry. 1997 Nov 25;36(47):14430-8. doi: 10.1021/bi970645k. Biochemistry. 1997. PMID: 9398161

4

Role of methionine 184 of human immunodeficiency virus type-1 reverse transcriptase in the polymerase function and fidelity of DNA synthesis.

Pandey VN, Kaushik N, Rege N, Sarafianos SG, Yadav PN, Modak MJ. Pandey VN, et al. Among authors: kaushik n. Biochemistry. 1996 Feb 20;35(7):2168-79. doi: 10.1021/bi9516642. Biochemistry. 1996. PMID: 8652558

5

Elucidation of the role of Arg 110 of murine leukemia virus reverse transcriptase in the catalytic mechanism: biochemical characterization of its mutant enzymes.

Chowdhury K, Kaushik N, Pandey VN, Modak MJ. Chowdhury K, et al. Among authors: kaushik n. Biochemistry. 1996 Dec 24;35(51):16610-20. doi: 10.1021/bi961462l. Biochemistry. 1996. PMID: 8987996

6

Polyamide nucleic acid targeted to the primer binding site of the HIV-1 RNA genome blocks in vitro HIV-1 reverse transcription.

Lee R, Kaushik N, Modak MJ, Vinayak R, Pandey VN. Lee R, et al. Among authors: kaushik n. Biochemistry. 1998 Jan 20;37(3):900-10. doi: 10.1021/bi972197m. Biochemistry. 1998. PMID: 9454580

7

Lysine 152 of MuLV reverse transcriptase is required for the integrity of the active site.

Shi Q, Singh K, Srivastava A, Kaushik N, Modak MJ. Shi Q, et al. Among authors: kaushik n. Biochemistry. 2002 Dec 17;41(50):14831-42. doi: 10.1021/bi0258389. Biochemistry. 2002. PMID: 12475231

8

Biochemical analysis of catalytically crucial aspartate mutants of human immunodeficiency virus type 1 reverse transcriptase.

Kaushik N, Rege N, Yadav PN, Sarafianos SG, Modak MJ, Pandey VN. Kaushik N, et al. Biochemistry. 1996 Sep 10;35(36):11536-46. doi: 10.1021/bi960364x. Biochemistry. 1996. PMID: 8794733

9

Role of glutamine 151 of human immunodeficiency virus type-1 reverse transcriptase in substrate selection as assessed by site-directed mutagenesis.

Kaushik N, Talele TT, Pandey PK, Harris D, Yadav PN, Pandey VN. Kaushik N, et al. Biochemistry. 2000 Mar 21;39(11):2912-20. doi: 10.1021/bi991376w. Biochemistry. 2000. PMID: 10715111

10

Tyrosine 222, a member of the YXDD motif of MuLV RT, is catalytically essential and is a major component of the fidelity center.

Kaushik N, Singh K, Alluru I, Modak MJ. Kaushik N, et al. Biochemistry. 1999 Mar 2;38(9):2617-27. doi: 10.1021/bi9824285. Biochemistry. 1999. PMID: 10052931

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