Chittenden T - Search Results

1

Bax interacts with the permeability transition pore to induce permeability transition and cytochrome c release in isolated mitochondria.

Narita M, Shimizu S, Ito T, Chittenden T, Lutz RJ, Matsuda H, Tsujimoto Y. Narita M, et al. Among authors: chittenden t. Proc Natl Acad Sci U S A. 1998 Dec 8;95(25):14681-6. doi: 10.1073/pnas.95.25.14681. Proc Natl Acad Sci U S A. 1998. PMID: 9843949 Free PMC article.

2

Bak BH3 peptides antagonize Bcl-xL function and induce apoptosis through cytochrome c-independent activation of caspases.

Holinger EP, Chittenden T, Lutz RJ. Holinger EP, et al. Among authors: chittenden t. J Biol Chem. 1999 May 7;274(19):13298-304. doi: 10.1074/jbc.274.19.13298. J Biol Chem. 1999. PMID: 10224090 Free article.

3

Expression of bbc3, a pro-apoptotic BH3-only gene, is regulated by diverse cell death and survival signals.

Han J, Flemington C, Houghton AB, Gu Z, Zambetti GP, Lutz RJ, Zhu L, Chittenden T. Han J, et al. Among authors: chittenden t. Proc Natl Acad Sci U S A. 2001 Sep 25;98(20):11318-23. doi: 10.1073/pnas.201208798. Proc Natl Acad Sci U S A. 2001. PMID: 11572983 Free PMC article.

4

Growth factors inactivate the cell death promoter BAD by phosphorylation of its BH3 domain on Ser155.

Zhou XM, Liu Y, Payne G, Lutz RJ, Chittenden T. Zhou XM, et al. Among authors: chittenden t. J Biol Chem. 2000 Aug 11;275(32):25046-51. doi: 10.1074/jbc.M002526200. J Biol Chem. 2000. PMID: 10837473 Free article.

5

A cytomegalovirus-encoded mitochondria-localized inhibitor of apoptosis structurally unrelated to Bcl-2.

Goldmacher VS, Bartle LM, Skaletskaya A, Dionne CA, Kedersha NL, Vater CA, Han JW, Lutz RJ, Watanabe S, Cahir McFarland ED, Kieff ED, Mocarski ES, Chittenden T. Goldmacher VS, et al. Among authors: chittenden t. Proc Natl Acad Sci U S A. 1999 Oct 26;96(22):12536-41. doi: 10.1073/pnas.96.22.12536. Proc Natl Acad Sci U S A. 1999. PMID: 10535957 Free PMC article.

6

Bik, a novel death-inducing protein shares a distinct sequence motif with Bcl-2 family proteins and interacts with viral and cellular survival-promoting proteins.

Boyd JM, Gallo GJ, Elangovan B, Houghton AB, Malstrom S, Avery BJ, Ebb RG, Subramanian T, Chittenden T, Lutz RJ, et al. Boyd JM, et al. Among authors: chittenden t. Oncogene. 1995 Nov 2;11(9):1921-8. Oncogene. 1995. PMID: 7478623

7

A conserved domain in Bak, distinct from BH1 and BH2, mediates cell death and protein binding functions.

Chittenden T, Flemington C, Houghton AB, Ebb RG, Gallo GJ, Elangovan B, Chinnadurai G, Lutz RJ. Chittenden T, et al. EMBO J. 1995 Nov 15;14(22):5589-96. doi: 10.1002/j.1460-2075.1995.tb00246.x. EMBO J. 1995. PMID: 8521816 Free PMC article.

8

Induction of apoptosis by the Bcl-2 homologue Bak.

Chittenden T, Harrington EA, O'Connor R, Flemington C, Lutz RJ, Evan GI, Guild BC. Chittenden T, et al. Nature. 1995 Apr 20;374(6524):733-6. doi: 10.1038/374733a0. Nature. 1995. PMID: 7715730

9

IMGN853, a Folate Receptor-α (FRα)-Targeting Antibody-Drug Conjugate, Exhibits Potent Targeted Antitumor Activity against FRα-Expressing Tumors.

Ab O, Whiteman KR, Bartle LM, Sun X, Singh R, Tavares D, LaBelle A, Payne G, Lutz RJ, Pinkas J, Goldmacher VS, Chittenden T, Lambert JM. Ab O, et al. Among authors: chittenden t. Mol Cancer Ther. 2015 Jul;14(7):1605-13. doi: 10.1158/1535-7163.MCT-14-1095. Epub 2015 Apr 22. Mol Cancer Ther. 2015. PMID: 25904506

10

A novel anti-CD37 antibody-drug conjugate with multiple anti-tumor mechanisms for the treatment of B-cell malignancies.

Deckert J, Park PU, Chicklas S, Yi Y, Li M, Lai KC, Mayo MF, Carrigan CN, Erickson HK, Pinkas J, Lutz RJ, Chittenden T, Lambert JM. Deckert J, et al. Among authors: chittenden t. Blood. 2013 Nov 14;122(20):3500-10. doi: 10.1182/blood-2013-05-505685. Epub 2013 Sep 3. Blood. 2013. PMID: 24002446 Free article.

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