Pedley RB - Search Results

1

Exemplifying guidelines for preparation of recombinant DNA products in phase I trials in cancer: preparation of a genetically engineered anti-CEA single chain Fv antibody.

Mayer A, Chester KA, Bhatia J, Pedley RB, Read DA, Boxer GM, Begent RH. Mayer A, et al. Among authors: pedley rb. Eur J Cancer. 1998 Jun;34(7):968-76. doi: 10.1016/s0959-8049(98)00035-5. Eur J Cancer. 1998. PMID: 9849442

2

In vivo tumor delivery of a recombinant single chain Fv::tumor necrosis factor-alpha fusion [correction of factor: a fusion] protein.

Cooke SP, Pedley RB, Boden R, Begent RH, Chester KA. Cooke SP, et al. Among authors: pedley rb. Bioconjug Chem. 2002 Jan-Feb;13(1):7-15. doi: 10.1021/bc000178a. Bioconjug Chem. 2002. PMID: 11792173

3

A single chain Fv derived from a filamentous phage library has distinct tumor targeting advantages over one derived from a hybridoma.

Verhaar MJ, Chester KA, Keep PA, Robson L, Pedley RB, Boden JA, Hawkins RE, Begent RH. Verhaar MJ, et al. Among authors: pedley rb. Int J Cancer. 1995 May 16;61(4):497-501. doi: 10.1002/ijc.2910610412. Int J Cancer. 1995. PMID: 7759155

4

Production and tumour-binding characterization of a chimeric anti-CEA Fab expressed in Escherichia coli.

Chester KA, Robson L, Keep PA, Pedley RB, Boden JA, Boxer GM, Hawkins RE, Begent RH. Chester KA, et al. Among authors: pedley rb. Int J Cancer. 1994 Apr 1;57(1):67-72. doi: 10.1002/ijc.2910570113. Int J Cancer. 1994. PMID: 8150543

5

Catalytic activity of an in vivo tumor targeted anti-CEA scFv::carboxypeptidase G2 fusion protein.

Bhatia J, Sharma SK, Chester KA, Pedley RB, Boden RW, Read DA, Boxer GM, Michael NP, Begent RH. Bhatia J, et al. Among authors: pedley rb. Int J Cancer. 2000 Feb 15;85(4):571-7. Int J Cancer. 2000. PMID: 10699932

6

Recombinant anti-carcinoembryonic antigen antibodies for targeting cancer.

Chester KA, Mayer A, Bhatia J, Robson L, Spencer DI, Cooke SP, Flynn AA, Sharma SK, Boxer G, Pedley RB, Begent RH. Chester KA, et al. Among authors: pedley rb. Cancer Chemother Pharmacol. 2000;46 Suppl:S8-12. doi: 10.1007/pl00014055. Cancer Chemother Pharmacol. 2000. PMID: 10950140 Review.

7

A strategy for antitumor vascular therapy by targeting the vascular endothelial growth factor: receptor complex.

Cooke SP, Boxer GM, Lawrence L, Pedley RB, Spencer DI, Begent RH, Chester KA. Cooke SP, et al. Among authors: pedley rb. Cancer Res. 2001 May 1;61(9):3653-9. Cancer Res. 2001. PMID: 11325835

8

Clinical applications of phage-derived sFvs and sFv fusion proteins.

Chester KA, Bhatia J, Boxer G, Cooke SP, Flynn AA, Huhalov A, Mayer A, Pedley RB, Robson L, Sharma SK, Spencer DI, Begent RH. Chester KA, et al. Among authors: pedley rb. Dis Markers. 2000;16(1-2):53-62. doi: 10.1155/2000/672706. Dis Markers. 2000. PMID: 11360829 Free PMC article. Review.

9

From laboratory to Phase I/II cancer trials with recombinant biotherapeutics.

Tolner B, Smith L, Hillyer T, Bhatia J, Beckett P, Robson L, Sharma SK, Griffin N, Vervecken W, Contreras R, Pedley RB, Begent RH, Chester KA. Tolner B, et al. Among authors: pedley rb. Eur J Cancer. 2007 Nov;43(17):2515-22. doi: 10.1016/j.ejca.2007.08.027. Epub 2007 Oct 22. Eur J Cancer. 2007. PMID: 17933516 Review.

10

A model-based approach for the optimization of radioimmunotherapy through antibody design and radionuclide selection.

Flynn AA, Green AJ, Pedley RB, Boxer GM, Dearling J, Watson R, Boden R, Begent RH. Flynn AA, et al. Among authors: pedley rb. Cancer. 2002 Feb 15;94(4 Suppl):1249-57. doi: 10.1002/cncr.10293. Cancer. 2002. PMID: 11877753 Free article.

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