Shen JC - Search Results

1

Werner syndrome protein. II. Characterization of the integral 3' --> 5' DNA exonuclease.

Kamath-Loeb AS, Shen JC, Loeb LA, Fry M. Kamath-Loeb AS, et al. Among authors: shen jc. J Biol Chem. 1998 Dec 18;273(51):34145-50. doi: 10.1074/jbc.273.51.34145. J Biol Chem. 1998. PMID: 9852074 Free article.

2

Mutations in the alpha8 loop of human APE1 alter binding and cleavage of DNA containing an abasic site.

Shen JC, Loeb LA. Shen JC, et al. J Biol Chem. 2003 Nov 21;278(47):46994-7001. doi: 10.1074/jbc.M309362200. Epub 2003 Sep 8. J Biol Chem. 2003. PMID: 12966083 Free article.

3

The N-terminal domain of the large subunit of human replication protein A binds to Werner syndrome protein and stimulates helicase activity.

Shen JC, Lao Y, Kamath-Loeb A, Wold MS, Loeb LA. Shen JC, et al. Mech Ageing Dev. 2003 Aug-Sep;124(8-9):921-30. doi: 10.1016/s0047-6374(03)00164-7. Mech Ageing Dev. 2003. PMID: 14499497

4

The Werner syndrome exonuclease facilitates DNA degradation and high fidelity DNA polymerization by human DNA polymerase δ.

Kamath-Loeb AS, Shen JC, Schmitt MW, Loeb LA. Kamath-Loeb AS, et al. Among authors: shen jc. J Biol Chem. 2012 Apr 6;287(15):12480-90. doi: 10.1074/jbc.M111.332577. Epub 2012 Feb 17. J Biol Chem. 2012. PMID: 22351772 Free PMC article.

5

Sphingosine, a modulator of human translesion DNA polymerase activity.

Kamath-Loeb AS, Balakrishna S, Whittington D, Shen JC, Emond MJ, Okabe T, Masutani C, Hanaoka F, Nishimura S, Loeb LA. Kamath-Loeb AS, et al. Among authors: shen jc. J Biol Chem. 2014 Aug 1;289(31):21663-72. doi: 10.1074/jbc.M114.570242. Epub 2014 Jun 13. J Biol Chem. 2014. PMID: 24928506 Free PMC article.

6

Unwinding the molecular basis of the Werner syndrome.

Shen J, Loeb LA. Shen J, et al. Mech Ageing Dev. 2001 Jul 15;122(9):921-44. doi: 10.1016/s0047-6374(01)00248-2. Mech Ageing Dev. 2001. PMID: 11348659 Review.

7

The Werner syndrome protein is a DNA helicase.

Gray MD, Shen JC, Kamath-Loeb AS, Blank A, Sopher BL, Martin GM, Oshima J, Loeb LA. Gray MD, et al. Among authors: shen jc. Nat Genet. 1997 Sep;17(1):100-3. doi: 10.1038/ng0997-100. Nat Genet. 1997. PMID: 9288107

8

Characterization of Werner syndrome protein DNA helicase activity: directionality, substrate dependence and stimulation by replication protein A.

Shen JC, Gray MD, Oshima J, Loeb LA. Shen JC, et al. Nucleic Acids Res. 1998 Jun 15;26(12):2879-85. doi: 10.1093/nar/26.12.2879. Nucleic Acids Res. 1998. PMID: 9611231 Free PMC article.

9

Werner syndrome protein. I. DNA helicase and dna exonuclease reside on the same polypeptide.

Shen JC, Gray MD, Oshima J, Kamath-Loeb AS, Fry M, Loeb LA. Shen JC, et al. J Biol Chem. 1998 Dec 18;273(51):34139-44. doi: 10.1074/jbc.273.51.34139. J Biol Chem. 1998. PMID: 9852073 Free article.

10

The Werner syndrome gene: the molecular basis of RecQ helicase-deficiency diseases.

Shen JC, Loeb LA. Shen JC, et al. Trends Genet. 2000 May;16(5):213-20. doi: 10.1016/s0168-9525(99)01970-8. Trends Genet. 2000. PMID: 10782115 Review.

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