Colson AO - Search Results

1

A hydrophobic cluster between transmembrane helices 5 and 6 constrains the thyrotropin-releasing hormone receptor in an inactive conformation.

Colson AO, Perlman JH, Jinsi-Parimoo A, Nussenzveig DR, Osman R, Gershengorn MC. Colson AO, et al. Mol Pharmacol. 1998 Dec;54(6):968-78. doi: 10.1124/mol.54.6.968. Mol Pharmacol. 1998. PMID: 9855624

2

Interactions between conserved residues in transmembrane helices 1, 2, and 7 of the thyrotropin-releasing hormone receptor.

Perlman JH, Colson AO, Wang W, Bence K, Osman R, Gershengorn MC. Perlman JH, et al. Among authors: colson ao. J Biol Chem. 1997 May 2;272(18):11937-42. doi: 10.1074/jbc.272.18.11937. J Biol Chem. 1997. PMID: 9115256 Free article.

3

Role of the extracellular loops of the thyrotropin-releasing hormone receptor: evidence for an initial interaction with thyrotropin-releasing hormone.

Perlman JH, Colson AO, Jain R, Czyzewski B, Cohen LA, Osman R, Gershengorn MC. Perlman JH, et al. Among authors: colson ao. Biochemistry. 1997 Dec 16;36(50):15670-6. doi: 10.1021/bi9713310. Biochemistry. 1997. PMID: 9398295

4

Static and dynamic roles of extracellular loops in G-protein-coupled receptors: a mechanism for sequential binding of thyrotropin-releasing hormone to its receptor.

Colson AO, Perlman JH, Smolyar A, Gershengorn MC, Osman R. Colson AO, et al. Biophys J. 1998 Mar;74(3):1087-100. doi: 10.1016/S0006-3495(98)77827-0. Biophys J. 1998. PMID: 9512011 Free PMC article.

5

Thyrotropin-releasing hormone analogs.

Colson AO, Gershengorn MC. Colson AO, et al. Mini Rev Med Chem. 2006 Feb;6(2):221-6. doi: 10.2174/138955706775476019. Mini Rev Med Chem. 2006. PMID: 16472189 Review.

6

Evaluation of small-molecule modulators of the luteinizing hormone/choriogonadotropin and thyroid stimulating hormone receptors: structure-activity relationships and selective binding patterns.

Moore S, Jaeschke H, Kleinau G, Neumann S, Costanzi S, Jiang JK, Childress J, Raaka BM, Colson A, Paschke R, Krause G, Thomas CJ, Gershengorn MC. Moore S, et al. J Med Chem. 2006 Jun 29;49(13):3888-96. doi: 10.1021/jm060247s. J Med Chem. 2006. PMID: 16789744 Free PMC article.

7

Efficacy, safety and tolerability of rozanolixizumab in patients with chronic inflammatory demyelinating polyradiculoneuropathy: a randomised, subject-blind, investigator-blind, placebo-controlled, phase 2a trial and open-label extension study.

Querol L, De Sèze J, Dysgaard T, Levine T, Rao TH, Rivner M, Hartung HP, Kiessling P, Shimizu S, Marmol D, Bozorg A, Colson AO, Massow U, Eftimov F; CIDP01 Study Investigators. Querol L, et al. Among authors: colson ao. J Neurol Neurosurg Psychiatry. 2024 Aug 16;95(9):845-854. doi: 10.1136/jnnp-2023-333112. J Neurol Neurosurg Psychiatry. 2024. PMID: 38729747 Free PMC article. Clinical Trial.

8

Evaluation and Application of a PET Tracer in Preclinical and Phase 1 Studies to Determine the Brain Biodistribution of Minzasolmin (UCB0599).

Mercier J, Bani M, Colson AO, Germani M, Lalla M, Plisson C, Huiban M, Searle G, Mathy FX, Nicholl R, Otoul C, Smit JW, van Asch V, Wagneur M, Maguire RP. Mercier J, et al. Among authors: colson ao. Mol Imaging Biol. 2024 Apr;26(2):310-321. doi: 10.1007/s11307-023-01878-7. Epub 2023 Dec 18. Mol Imaging Biol. 2024. PMID: 38110790 Free PMC article. Clinical Trial.

9

Brivaracetam-induced elevation of carbamazepine epoxide levels: A post-hoc analysis from the clinical development program.

Brodie MJ, Fakhoury T, McDonough B, Colson AO, Stockis A, Elmoufti S, Whitesides J. Brodie MJ, et al. Among authors: colson ao. Epilepsy Res. 2018 Sep;145:55-62. doi: 10.1016/j.eplepsyres.2018.06.002. Epub 2018 Jun 4. Epilepsy Res. 2018. PMID: 29908435 Clinical Trial.

10

Discovery of orally bioavailable 1,3,4-trisubstituted 2-oxopiperazine-based melanocortin-4 receptor agonists as potential antiobesity agents.

Tian X, Switzer AG, Derose SA, Mishra RK, Solinsky MG, Mumin RN, Ebetino FH, Jayasinghe LR, Webster ME, Colson AO, Crossdoersen D, Pinney BB, Farmer JA, Dowty ME, Obringer CM, Cruze CA, Burklow ML, Suchanek PM, Dong L, Dirr MK, Sheldon RJ, Wos JA. Tian X, et al. Among authors: colson ao. J Med Chem. 2008 Oct 9;51(19):6055-66. doi: 10.1021/jm800525p. Epub 2008 Sep 5. J Med Chem. 2008. PMID: 18771254

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