Nussenzveig DR - Search Results

1

A hydrophobic cluster between transmembrane helices 5 and 6 constrains the thyrotropin-releasing hormone receptor in an inactive conformation.

Colson AO, Perlman JH, Jinsi-Parimoo A, Nussenzveig DR, Osman R, Gershengorn MC. Colson AO, et al. Among authors: nussenzveig dr. Mol Pharmacol. 1998 Dec;54(6):968-78. doi: 10.1124/mol.54.6.968. Mol Pharmacol. 1998. PMID: 9855624

2

Thyrotropin-releasing hormone binding to the mouse pituitary receptor does not involve ionic interactions. A model for neutral peptide binding to G protein-coupled receptors.

Perlman JH, Nussenzveig DR, Osman R, Gershengorn MC. Perlman JH, et al. Among authors: nussenzveig dr. J Biol Chem. 1992 Dec 5;267(34):24413-7. J Biol Chem. 1992. PMID: 1332958 Free article.

3

A disulfide bond between conserved extracellular cysteines in the thyrotropin-releasing hormone receptor is critical for binding.

Perlman JH, Wang W, Nussenzveig DR, Gershengorn MC. Perlman JH, et al. Among authors: nussenzveig dr. J Biol Chem. 1995 Oct 20;270(42):24682-5. doi: 10.1074/jbc.270.42.24682. J Biol Chem. 1995. PMID: 7559582 Free article.

4

Expression of thyrotropin-releasing hormone receptors by adenovirus-mediated gene transfer reveals that thyrotropin-releasing hormone desensitization is cell specific.

Falck-Pedersen E, Heinflink M, Alvira M, Nussenzveig DR, Gershengorn MC. Falck-Pedersen E, et al. Among authors: nussenzveig dr. Mol Pharmacol. 1994 Apr;45(4):684-9. Mol Pharmacol. 1994. PMID: 8183247

5

Decreased levels of internalized thyrotropin-releasing hormone receptors after uncoupling from guanine nucleotide-binding protein and phospholipase-C.

Nussenzveig DR, Heinflink M, Gershengorn MC. Nussenzveig DR, et al. Mol Endocrinol. 1993 Sep;7(9):1105-11. doi: 10.1210/mend.7.9.8247012. Mol Endocrinol. 1993. PMID: 8247012

6

Agonist-stimulated internalization of the thyrotropin-releasing hormone receptor is dependent on two domains in the receptor carboxyl terminus.

Nussenzveig DR, Heinflink M, Gershengorn MC. Nussenzveig DR, et al. J Biol Chem. 1993 Feb 5;268(4):2389-92. J Biol Chem. 1993. PMID: 8381407 Free article.

7

A constitutively active mutant thyrotropin-releasing hormone receptor is chronically down-regulated in pituitary cells: evidence using chlordiazepoxide as a negative antagonist.

Heinflink M, Nussenzveig DR, Grimberg H, Lupu-Meiri M, Oron Y, Gershengorn MC. Heinflink M, et al. Among authors: nussenzveig dr. Mol Endocrinol. 1995 Nov;9(11):1455-60. doi: 10.1210/mend.9.11.8584022. Mol Endocrinol. 1995. PMID: 8584022

8

The hemispheric functional expression of the thyrotropin-releasing-hormone receptor is not determined by the receptors' physical distribution.

Matus-Leibovitch N, Nussenzveig DR, Gershengorn MC, Oron Y. Matus-Leibovitch N, et al. Among authors: nussenzveig dr. Biochem J. 1994 Oct 1;303 ( Pt 1)(Pt 1):129-34. doi: 10.1042/bj3030129. Biochem J. 1994. PMID: 7524480 Free PMC article.

9

Desensitization of the response to thyrotropin-releasing hormone in Xenopus oocytes is an amplified process that precedes calcium mobilization.

Lipinsky D, Nussenzveig DR, Gershengorn MC, Oron Y. Lipinsky D, et al. Among authors: nussenzveig dr. Pflugers Arch. 1995 Jan;429(3):419-25. doi: 10.1007/BF00374158. Pflugers Arch. 1995. PMID: 7539127

10

Truncation of the thyrotropin-releasing hormone receptor carboxyl tail causes constitutive activity and leads to impaired responsiveness in Xenopus oocytes and AtT20 cells.

Matus-Leibovitch N, Nussenzveig DR, Gershengorn MC, Oron Y. Matus-Leibovitch N, et al. Among authors: nussenzveig dr. J Biol Chem. 1995 Jan 20;270(3):1041-7. doi: 10.1074/jbc.270.3.1041. J Biol Chem. 1995. PMID: 7836357 Free article.

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