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Aberrant hippocampal Ca2+ micro-waves following synapsin-dependent adeno-associated viral expression of Ca2+ indicators.
Masala N, Mittag M, Giovannetti EA, O'Neil DA, Distler F, Rupprecht P, Helmchen F, Yuste R, Fuhrmann M, Beck H, Wenzel M, Kelly T. Masala N, et al. Among authors: helmchen f. bioRxiv [Preprint]. 2024 Jan 30:2023.11.08.566169. doi: 10.1101/2023.11.08.566169. bioRxiv. 2024. Update in: Elife. 2024 Jul 23;13:RP93804. doi: 10.7554/eLife.93804. PMID: 37986838 Free PMC article. Updated. Preprint.
Striatum-projecting prefrontal cortex neurons support working memory maintenance.
Wilhelm M, Sych Y, Fomins A, Alatorre Warren JL, Lewis C, Serratosa Capdevila L, Boehringer R, Amadei EA, Grewe B, O'Connor EC, Hall BJ, Helmchen F. Wilhelm M, et al. Among authors: helmchen f. Nat Commun. 2023 Nov 2;14(1):7016. doi: 10.1038/s41467-023-42777-3. Nat Commun. 2023. PMID: 37919287 Free PMC article.
Whole-mouse clearing and imaging at the cellular level with vDISCO.
Cai R, Kolabas ZI, Pan C, Mai H, Zhao S, Kaltenecker D, Voigt FF, Molbay M, Ohn TL, Vincke C, Todorov MI, Helmchen F, Van Ginderachter JA, Ertürk A. Cai R, et al. Among authors: helmchen f. Nat Protoc. 2023 Apr;18(4):1197-1242. doi: 10.1038/s41596-022-00788-2. Epub 2023 Jan 25. Nat Protoc. 2023. PMID: 36697871 Review.
Reflective multi-immersion microscope objectives inspired by the Schmidt telescope.
Voigt FF, Reuss AM, Naert T, Hildebrand S, Schaettin M, Hotz AL, Whitehead L, Bahl A, Neuhauss SCF, Roebroeck A, Stoeckli ET, Lienkamp SS, Aguzzi A, Helmchen F. Voigt FF, et al. Among authors: helmchen f. Nat Biotechnol. 2024 Jan;42(1):65-71. doi: 10.1038/s41587-023-01717-8. Epub 2023 Mar 30. Nat Biotechnol. 2024. PMID: 36997681 Free PMC article.
Whole-brain microscopy reveals distinct temporal and spatial efficacy of anti-Aβ therapies.
Kirschenbaum D, Dadgar-Kiani E, Catto F, Voigt FF, Trevisan C, Bichsel O, Shirani H, Nilsson KPR, Frontzek KJ, Paganetti P, Helmchen F, Lee JH, Aguzzi A. Kirschenbaum D, et al. Among authors: helmchen f. EMBO Mol Med. 2023 Jan 11;15(1):e16789. doi: 10.15252/emmm.202216789. Epub 2022 Nov 16. EMBO Mol Med. 2023. PMID: 36382364 Free PMC article.
158 results