Le Roch M - Search Results

1

Solid phase organic synthesis of polyamine derivatives and initial biological evaluation of their antitumoral activity.

Tomasi S, Le Roch M, Renault J, Corbel JC, Uriac P, Carboni B, Moncoq D, Martin B, Delcros JG. Tomasi S, et al. Among authors: le roch m. Bioorg Med Chem Lett. 1998 Mar 17;8(6):635-40. doi: 10.1016/s0960-894x(98)00086-9. Bioorg Med Chem Lett. 1998. PMID: 9871574

2

Toxicity and osmoprotective activities of analogues of glycine betaine obtained by solid phase organic synthesis towards Sinorhizobium meliloti.

Cosquer A, Pichereau V, Le Mée D, Le Roch M, Renault J, Carboni B, Uriac P, Bernard T. Cosquer A, et al. Among authors: le mee d, le roch m. Bioorg Med Chem Lett. 1999 Jan 4;9(1):49-54. doi: 10.1016/s0960-894x(98)00679-9. Bioorg Med Chem Lett. 1999. PMID: 9990455

3

Molecular analyses of the combining site of the anti-spermine monoclonal antibody Spm8-2.

Bouillé N, Johnston J, Debroise I, Royou A, Le Roch M, Renault J, Moulinoux JP, Delcros JG. Bouillé N, et al. Among authors: le roch m. Biochem Soc Trans. 1998 Nov;26(4):S368. doi: 10.1042/bst026s368. Biochem Soc Trans. 1998. PMID: 10047882 No abstract available.

4

Molecular analysis of the combining site of a monoclonal antibody against spermine.

Bouillé N, Johnston J, Royou A, Debroise I, Le Roch M, Renault J, Moulinoux JP, Delcros JG. Bouillé N, et al. Among authors: le roch m. Mol Immunol. 1999 Feb;36(2):93-102. doi: 10.1016/s0161-5890(99)00025-5. Mol Immunol. 1999. PMID: 10378681

5

Solid phase synthesis of sulphonamides: novel ligands of 5-HT6 receptors.

Renault J, Fabis F, Dauphin F, Lebranchu M, Le Roch M, Butt S, Uriac P, Rault S. Renault J, et al. Among authors: le roch m. J Pharm Pharmacol. 2001 Jul;53(7):969-72. doi: 10.1211/0022357011776207. J Pharm Pharmacol. 2001. PMID: 11480548

6

Parallel supported synthesis of polyamine-imidazole conjugates.

Picard S, Le Roch M, Renault J, Uriac P. Picard S, et al. Among authors: le roch m. Org Lett. 2004 Dec 9;6(25):4711-4. doi: 10.1021/ol0480630. Org Lett. 2004. PMID: 15575667

7

Synthesis of a laterally branched polyamine from alpha-methylene-gamma-butyrolactone.

Jean M, Le Roch M, Renault J, Uriac P. Jean M, et al. Among authors: le roch m. Org Lett. 2005 Jun 23;7(13):2663-5. doi: 10.1021/ol050803x. Org Lett. 2005. PMID: 15957916

8

Effect of polyamine homologation on the transport and biological properties of heterocyclic amidines.

Delcros JG, Tomasi S, Duhieu S, Foucault M, Martin B, Le Roch M, Eifler-Lima V, Renault J, Uriac P. Delcros JG, et al. Among authors: le roch m. J Med Chem. 2006 Jan 12;49(1):232-45. doi: 10.1021/jm050018q. J Med Chem. 2006. PMID: 16392808

9

Synthesis of substituted pyrrolin-4-ones from amino acids in mild conditions via a gold-catalyzed approach.

Gouault N, Le Roch M, Cornée C, David M, Uriac P. Gouault N, et al. Among authors: le roch m. J Org Chem. 2009 Aug 7;74(15):5614-7. doi: 10.1021/jo900693a. J Org Chem. 2009. PMID: 19514745

10

Targeting the polyamine transport system with benzazepine- and azepine-polyamine conjugates.

Tomasi S, Renault J, Martin B, Duhieu S, Cerec V, Le Roch M, Uriac P, Delcros JG. Tomasi S, et al. Among authors: le roch m. J Med Chem. 2010 Nov 11;53(21):7647-63. doi: 10.1021/jm1007648. J Med Chem. 2010. PMID: 20925391

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