Lee KH - Search Results

1

Antitumor agents. Part 186: Synthesis and biological evaluation of demethylcolchiceinamide analogues as cytotoxic DNA topoisomerase II inhibitors.

Guan J, Zhu XK, Tachibana Y, Bastow KF, Brossi A, Hamel E, Lee KH. Guan J, et al. Among authors: lee kh. Bioorg Med Chem. 1998 Nov;6(11):2127-31. doi: 10.1016/s0968-0896(98)00165-5. Bioorg Med Chem. 1998. PMID: 9881102

2

Antiproliferative actions of 7-substituted 1,3-dihydroxyacridones; possible involvement of DNA topoisomerase II and protein kinase C as biochemical targets.

Bastow KF, Itoigawa M, Furukawa H, Kashiwada Y, Bori ID, Ballas LM, Lee KH. Bastow KF, et al. Among authors: lee kh. Bioorg Med Chem. 1994 Dec;2(12):1403-11. doi: 10.1016/s0968-0896(00)82092-1. Bioorg Med Chem. 1994. PMID: 7788303

3

Antitumor agents. 155. Synthesis and biological evaluation of 3',6,7-substituted 2-phenyl-4-quinolones as antimicrotubule agents.

Li L, Wang HK, Kuo SC, Wu TS, Mauger A, Lin CM, Hamel E, Lee KH. Li L, et al. Among authors: lee kh. J Med Chem. 1994 Sep 30;37(20):3400-7. doi: 10.1021/jm00046a025. J Med Chem. 1994. PMID: 7932568

4

Synthesis and biological evaluation of tetrademethyl isocolchicine derivatives as inhibitors of DNA topoisomerase action in vitro.

Bastow KF, Tatematsu H, Sun L, Fukushima Y, Lee KH. Bastow KF, et al. Among authors: lee kh. Bioorg Med Chem. 1993 Sep;1(3):227-34. doi: 10.1016/s0968-0896(00)82125-2. Bioorg Med Chem. 1993. PMID: 8081856

5

Antitumor agents. 150. 2',3',4',5',5,6,7-substituted 2-phenyl-4-quinolones and related compounds: their synthesis, cytotoxicity, and inhibition of tubulin polymerization.

Li L, Wang HK, Kuo SC, Wu TS, Lednicer D, Lin CM, Hamel E, Lee KH. Li L, et al. Among authors: lee kh. J Med Chem. 1994 Apr 15;37(8):1126-35. doi: 10.1021/jm00034a010. J Med Chem. 1994. PMID: 8164254

6

Antitumor agents. 141. Synthesis and biological evaluation of novel thiocolchicine analogs: N-acyl-, N-aroyl-, and N-(substituted benzyl)deacetylthiocolchicines as potent cytotoxic and antimitotic compounds.

Sun L, Hamel E, Lin CM, Hastie SB, Pyluck A, Lee KH. Sun L, et al. Among authors: lee kh. J Med Chem. 1993 May 14;36(10):1474-9. doi: 10.1021/jm00062a021. J Med Chem. 1993. PMID: 8496915

7

Antitumor agents. 139. Synthesis and biological evaluation of thiocolchicine analogs 5,6-dihydro-6(S)-(acyloxy)- and 5,6-dihydro-6(S)-[(aroyloxy)methyl]-1,2,3-trimethoxy-9-(methylthio)-8H- cyclohepta[a]naphthalen-8-ones as novel cytotoxic and antimitotic agents.

Sun L, McPhail AT, Hamel E, Lin CM, Hastie SB, Chang JJ, Lee KH. Sun L, et al. Among authors: lee kh. J Med Chem. 1993 Mar 5;36(5):544-51. doi: 10.1021/jm00057a004. J Med Chem. 1993. PMID: 8496935

8

Antitumor agents. 166. Synthesis and biological evaluation of 5,6,7,8-substituted-2-phenylthiochromen-4-ones.

Wang HK, Bastow KF, Cosentino LM, Lee KH. Wang HK, et al. Among authors: lee kh. J Med Chem. 1996 May 10;39(10):1975-80. doi: 10.1021/jm960008c. J Med Chem. 1996. PMID: 8642556

9

Antitumor agents. 164. Podophenazine, 2'',3''-dichloropodophenazine, benzopodophenazine, and their 4 beta-p-nitroaniline derivatives as novel DNA topoisomerase II inhibitors.

Cho SJ, Kashiwada Y, Bastow KF, Cheng YC, Lee KH. Cho SJ, et al. Among authors: lee kh. J Med Chem. 1996 Mar 29;39(7):1396-402. doi: 10.1021/jm950548u. J Med Chem. 1996. PMID: 8691469

10

Antitumor agents. 172. Synthesis and biological evaluation of novel deacetamidothiocolchicin-7-ols and ester analogs as antitubulin agents.

Shi Q, Verdier-Pinard P, Brossi A, Hamel E, McPhail AT, Lee KH. Shi Q, et al. Among authors: lee kh. J Med Chem. 1997 Mar 14;40(6):961-6. doi: 10.1021/jm960663k. J Med Chem. 1997. PMID: 9083485

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