Lai Z - Search Results

1

Characterization of the transthyretin acid denaturation pathways by analytical ultracentrifugation: implications for wild-type, V30M, and L55P amyloid fibril formation.

Lashuel HA, Lai Z, Kelly JW. Lashuel HA, et al. Among authors: lai z. Biochemistry. 1998 Dec 22;37(51):17851-64. doi: 10.1021/bi981876+. Biochemistry. 1998. PMID: 9922152

2

Comparison of lethal and nonlethal transthyretin variants and their relationship to amyloid disease.

McCutchen SL, Lai Z, Miroy GJ, Kelly JW, Colón W. McCutchen SL, et al. Among authors: lai z. Biochemistry. 1995 Oct 17;34(41):13527-36. doi: 10.1021/bi00041a032. Biochemistry. 1995. PMID: 7577941

3

The acid-mediated denaturation pathway of transthyretin yields a conformational intermediate that can self-assemble into amyloid.

Lai Z, Colón W, Kelly JW. Lai Z, et al. Biochemistry. 1996 May 21;35(20):6470-82. doi: 10.1021/bi952501g. Biochemistry. 1996. PMID: 8639594

4

Inhibiting transthyretin amyloid fibril formation via protein stabilization.

Miroy GJ, Lai Z, Lashuel HA, Peterson SA, Strang C, Kelly JW. Miroy GJ, et al. Among authors: lai z. Proc Natl Acad Sci U S A. 1996 Dec 24;93(26):15051-6. doi: 10.1073/pnas.93.26.15051. Proc Natl Acad Sci U S A. 1996. PMID: 8986762 Free PMC article.

5

Guanidine hydrochloride-induced denaturation and refolding of transthyretin exhibits a marked hysteresis: equilibria with high kinetic barriers.

Lai Z, McCulloch J, Lashuel HA, Kelly JW. Lai Z, et al. Biochemistry. 1997 Aug 19;36(33):10230-9. doi: 10.1021/bi963195p. Biochemistry. 1997. PMID: 9254621

6

Transthyretin quaternary and tertiary structural changes facilitate misassembly into amyloid.

Kelly JW, Colon W, Lai Z, Lashuel HA, McCulloch J, McCutchen SL, Miroy GJ, Peterson SA. Kelly JW, et al. Among authors: lai z. Adv Protein Chem. 1997;50:161-81. doi: 10.1016/s0065-3233(08)60321-6. Adv Protein Chem. 1997. PMID: 9338081 Review.

7

FAP mutations destabilize transthyretin facilitating conformational changes required for amyloid formation.

Colon W, Lai Z, McCutchen SL, Miroy GJ, Strang C, Kelly JW. Colon W, et al. Among authors: lai z. Ciba Found Symp. 1996;199:228-38; discussion 239-42. doi: 10.1002/9780470514924.ch14. Ciba Found Symp. 1996. PMID: 8915613

8

Protein subunit interactions and structural integrity of amyloidogenic transthyretins: evidence from electrospray mass spectrometry.

Nettleton EJ, Sunde M, Lai Z, Kelly JW, Dobson CM, Robinson CV. Nettleton EJ, et al. Among authors: lai z. J Mol Biol. 1998 Aug 21;281(3):553-64. doi: 10.1006/jmbi.1998.1937. J Mol Biol. 1998. PMID: 9698569

9

Metal and RNA binding properties of the hdm2 RING finger domain.

Lai Z, Freedman DA, Levine AJ, McLendon GL. Lai Z, et al. Biochemistry. 1998 Dec 1;37(48):17005-15. Biochemistry. 1998. PMID: 9882094 No abstract available.

10

Metal and RNA binding properties of the hdm2 RING finger domain.

Lai Z, Freedman DA, Levine AJ, McLendon GL. Lai Z, et al. Biochemistry. 1998 Dec 1;37(48):7005-15. doi: 10.1021/bi980596r. Biochemistry. 1998. PMID: 9836595

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