Roques BP - Search Results

1

The prosequence of thermolysin acts as an intramolecular chaperone when expressed in trans with the mature sequence in Escherichia coli.

Marie-Claire C, Ruffet E, Beaumont A, Roques BP. Marie-Claire C, et al. Among authors: roques bp. J Mol Biol. 1999 Feb 5;285(5):1911-5. doi: 10.1006/jmbi.1998.2449. J Mol Biol. 1999. PMID: 9925774

2

Evidence by site-directed mutagenesis that arginine 203 of thermolysin and arginine 717 of neprilysin (neutral endopeptidase) play equivalent critical roles in substrate hydrolysis and inhibitor binding.

Marie-Claire C, Ruffet E, Antonczak S, Beaumont A, O'Donohue M, Roques BP, Fournié-Zaluski MC. Marie-Claire C, et al. Among authors: roques bp. Biochemistry. 1997 Nov 11;36(45):13938-45. doi: 10.1021/bi9712495. Biochemistry. 1997. PMID: 9374873

3

Intramolecular processing of prothermolysin.

Marie-Claire C, Roques BP, Beaumont A. Marie-Claire C, et al. Among authors: roques bp. J Biol Chem. 1998 Mar 6;273(10):5697-701. doi: 10.1074/jbc.273.10.5697. J Biol Chem. 1998. PMID: 9488701 Free article.

4

Cloning and expression in Bacillus subtilis of the npr gene from Bacillus thermoproteolyticus Rokko coding for the thermostable metalloprotease thermolysin.

O'Donohue MJ, Roques BP, Beaumont A. O'Donohue MJ, et al. Among authors: roques bp. Biochem J. 1994 Jun 1;300 ( Pt 2)(Pt 2):599-603. doi: 10.1042/bj3000599. Biochem J. 1994. PMID: 8002967 Free PMC article.

5

Characterization of Glu350 as a critical residue involved in the N-terminal amine binding site of aminopeptidase N (EC 3.4.11.2): insights into its mechanism of action.

Luciani N, Marie-Claire C, Ruffet E, Beaumont A, Roques BP, Fournié-Zaluski MC. Luciani N, et al. Among authors: roques bp. Biochemistry. 1998 Jan 13;37(2):686-92. doi: 10.1021/bi971705p. Biochemistry. 1998. PMID: 9425092

6

Exploration of the S(')(1) subsite of neprilysin: a joined molecular modeling and site-directed mutagenesis study.

Marie-Claire C, Tiraboschi G, Ruffet E, Inguimbert N, Fournie-Zaluski MC, Roques BP. Marie-Claire C, et al. Among authors: roques bp. Proteins. 2000 Jun 1;39(4):365-71. doi: 10.1002/(sici)1097-0134(20000601)39:4<365::aid-prot90>3.0.co;2-t. Proteins. 2000. PMID: 10813818

7

Neutral endopeptidase-24.11 inhibitors: from analgesics to antihypertensives?

Roques BP, Beaumont A. Roques BP, et al. Trends Pharmacol Sci. 1990 Jun;11(6):245-9. doi: 10.1016/0165-6147(90)90252-4. Trends Pharmacol Sci. 1990. PMID: 2166369 Review.

8

Irreversible photolabeling of active site of neutral endopeptidase-24.11 "enkephalinase" by azidothiorphan and [14C]-azidothiorphan.

Beaumont A, Hernandez JF, Chaillet P, Crine P, Roques BP. Beaumont A, et al. Among authors: roques bp. Mol Pharmacol. 1987 Nov;32(5):594-9. Mol Pharmacol. 1987. PMID: 3479679

9

The role of histidine 231 in thermolysin-like enzymes. A site-directed mutagenesis study.

Beaumont A, O'Donohue MJ, Paredes N, Rousselet N, Assicot M, Bohuon C, Fournié-Zaluski MC, Roques BP. Beaumont A, et al. Among authors: roques bp. J Biol Chem. 1995 Jul 14;270(28):16803-8. doi: 10.1074/jbc.270.28.16803. J Biol Chem. 1995. PMID: 7622493 Free article.

10

Further evidence that the CCK2 receptor is coupled to two transduction pathways using site-directed mutagenesis.

Pommier B, Marie-Claire C, Da Nascimento S, Wang HL, Roques BP, Noble F. Pommier B, et al. Among authors: roques bp. J Neurochem. 2003 Apr;85(2):454-61. doi: 10.1046/j.1471-4159.2003.01690.x. J Neurochem. 2003. PMID: 12675921 Free article.

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