Ford H Jr - Search Results

1

Dynamics of the antiviral activity of N-methanocarbathymidine against herpes simplex virus type 1 in cell culture.

Huleihel M, Talishanisky M, Ford H Jr, Marquez VE, Kelley JA, Johns DG, Agbaria R. Huleihel M, et al. Among authors: ford h jr. Int J Antimicrob Agents. 2005 May;25(5):427-32. doi: 10.1016/j.ijantimicag.2005.01.013. Int J Antimicrob Agents. 2005. PMID: 15848299

2

Antitumor activity and metabolic activation of N-methanocarbathymidine, a novel thymidine analogue with a pseudosugar rigidly fixed in the northern conformation, in murine colon cancer cells expressing herpes simplex thymidine kinase.

Noy R, Ben-Zvi Z, Manor E, Candotti F, Morris JC, Ford H Jr, Marquez VE, Johns DG, Agbaria R. Noy R, et al. Among authors: ford h jr. Mol Cancer Ther. 2002 Jun;1(8):585-93. Mol Cancer Ther. 2002. PMID: 12479218

3

Pharmacokinetics and organ distribution of N-methanocarbathymidine, a novel thymidine analog, in mice bearing tumors transduced with the herpes simplex thymidine kinase gene.

Noy R, Ben-Zvi Z, Elezra M, Candotti F, Ford H Jr, Morris JC, Marquez VE, Johns DG, Agbaria R. Noy R, et al. Among authors: ford h jr. Cancer Chemother Pharmacol. 2002 Nov;50(5):360-6. doi: 10.1007/s00280-002-0505-8. Epub 2002 Sep 20. Cancer Chemother Pharmacol. 2002. PMID: 12439593

4

Metabolic pathways of N-methanocarbathymidine, a novel antiviral agent, in native and herpes simplex virus type 1 infected Vero cells.

Zalah L, Huleihel M, Manor E, Konson A, Ford H Jr, Marquez VE, Johns DG, Agbaria R. Zalah L, et al. Among authors: ford h jr. Antiviral Res. 2002 Jul;55(1):63-75. doi: 10.1016/s0166-3542(02)00010-4. Antiviral Res. 2002. PMID: 12076752

5

Is the anomeric effect an important factor in the rate of adenosine deaminase catalyzed hydrolysis of purine nucleosides? A direct comparison of nucleoside analogues constructed on ribose and carbocyclic templates with equivalent heterocyclic bases selected to promote hydration.

Hernandez S, Ford H Jr, Marquez VE. Hernandez S, et al. Among authors: ford h jr. Bioorg Med Chem. 2002 Aug;10(8):2723-30. doi: 10.1016/s0968-0896(02)00099-8. Bioorg Med Chem. 2002. PMID: 12057661

6

Biosynthetic ganciclovir triphosphate: its isolation and characterization from ganciclovir-treated herpes simplex thymidine kinase-transduced murine cells.

Agbaria R, Candotti F, Kelley JA, Hao Z, Johns DG, Cooney DA, Blaese RM, Ford H Jr. Agbaria R, et al. Among authors: ford h jr. Biochem Biophys Res Commun. 2001 Nov 30;289(2):525-30. doi: 10.1006/bbrc.2001.6011. Biochem Biophys Res Commun. 2001. PMID: 11716505

7

Evaluation of a fluorogenic derivatization method for the reversed-phase HPLC analysis of 2'-beta-fluoro-2',3'-dideoxyadenosine, a new anti-AIDS drug.

Zhang H, Ford H Jr, Roth JS, Kelley JA. Zhang H, et al. Among authors: ford h jr. J Pharm Biomed Anal. 2001 May;25(2):285-97. doi: 10.1016/s0731-7085(00)00496-9. J Pharm Biomed Anal. 2001. PMID: 11275436

8

Fluorometric determination of 2'-beta-fluoro-2',3'-dideoxyadenosine 5'-triphosphate, the active metabolite of a new anti-human immunodeficiency virus drug, in human lymphocytes.

Dai F, Kelley JA, Zhang H, Malinowski N, Kavlick MF, Lietzau J, Welles L, Yarchoan R, Ford H Jr. Dai F, et al. Among authors: ford h jr. Anal Biochem. 2001 Jan 1;288(1):52-61. doi: 10.1006/abio.2000.4862. Anal Biochem. 2001. PMID: 11141306

9

A remarkably simple chemicoenzymatic approach to structurally complex bicyclo[3.1.0]hexane carbocyclic nucleosides.

Moon HR, Ford H Jr, Marquez VE. Moon HR, et al. Among authors: ford h jr. Org Lett. 2000 Nov 30;2(24):3793-6. doi: 10.1021/ol000238s. Org Lett. 2000. PMID: 11101421

10

Interactions of conformationally biased north and south 2'-fluoro-2', 3'-dideoxynucleoside 5'-triphosphates with the active site of HIV-1 reverse transcriptase.

Mu L, Sarafianos SG, Nicklaus MC, Russ P, Siddiqui MA, Ford H Jr, Mitsuya H, Le R, Kodama E, Meier C, Knispel T, Anderson L, Barchi JJ Jr, Marquez VE. Mu L, et al. Among authors: ford h jr. Biochemistry. 2000 Sep 19;39(37):11205-15. doi: 10.1021/bi001090n. Biochemistry. 2000. PMID: 10985766

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