Shirouzu M - Search Results

1

Nuclear magnetic resonance and molecular dynamics studies on the interactions of the Ras-binding domain of Raf-1 with wild-type and mutant Ras proteins.

Terada T, Ito Y, Shirouzu M, Tateno M, Hashimoto K, Kigawa T, Ebisuzaki T, Takio K, Shibata T, Yokoyama S, Smith BO, Laue ED, Cooper JA. Terada T, et al. Among authors: shirouzu m. J Mol Biol. 1999 Feb 12;286(1):219-32. doi: 10.1006/jmbi.1998.2472. J Mol Biol. 1999. PMID: 9931261

2

A glutamic acid residue at position 31 of Ras protein is essential to the signal transduction for neurite outgrowth of PC12 cells and the stimulation of GTPase activity by GAPRas.

Shirouzu M, Fujita-Yoshigaki J, Ito Y, Koide H, Nishimura S, Yokoyama S. Shirouzu M, et al. Oncogene. 1992 Mar;7(3):475-80. Oncogene. 1992. PMID: 1549361

3

Identification of amino acid residues of Ras protein that are essential for signal-transducing activity but not for enhancement of GTPase activity by GAP.

Fujita-Yoshigaki J, Shirouzu M, Koide H, Nishimura S, Yokoyama S. Fujita-Yoshigaki J, et al. Among authors: shirouzu m. FEBS Lett. 1991 Dec 9;294(3):187-90. doi: 10.1016/0014-5793(91)80665-p. FEBS Lett. 1991. PMID: 1756860 Free article.

4

A constitutive effector region on the C-terminal side of switch I of the Ras protein.

Fujita-Yoshigaki J, Shirouzu M, Ito Y, Hattori S, Furuyama S, Nishimura S, Yokoyama S. Fujita-Yoshigaki J, et al. Among authors: shirouzu m. J Biol Chem. 1995 Mar 3;270(9):4661-7. doi: 10.1074/jbc.270.9.4661. J Biol Chem. 1995. PMID: 7876237 Free article.

As for a region on the C-terminal side of switch I, the V45E and G48C mutants of Ras failed to promote neurite outgrowth of PC12 cells (Fujita-Yoshigaki, J., Shirouzu, M., Koide, H., Nishimura, S., and Yokoyama, S. (1991) FEBS Lett. 294, 187-190). ...Therefore, the …

As for a region on the C-terminal side of switch I, the V45E and G48C mutants of Ras failed to promote neurite outgrowth of PC12 cells (Fuji …

5

Mutations that abolish the ability of Ha-Ras to associate with Raf-1.

Shirouzu M, Koide H, Fujita-Yoshigaki J, Oshio H, Toyama Y, Yamasaki K, Fuhrman SA, Villafranca E, Kaziro Y, Yokoyama S. Shirouzu M, et al. Oncogene. 1994 Aug;9(8):2153-7. Oncogene. 1994. PMID: 8036000

6

Site-directed mutagenesis, fluorescence, and two-dimensional NMR studies on microenvironments of effector region aromatic residues of human c-Ha-Ras protein.

Yamasaki K, Shirouzu M, Muto Y, Fujita-Yoshigaki J, Koide H, Ito Y, Kawai G, Hattori S, Yokoyama S, Nishimura S, et al. Yamasaki K, et al. Among authors: shirouzu m. Biochemistry. 1994 Jan 11;33(1):65-73. doi: 10.1021/bi00167a009. Biochemistry. 1994. PMID: 8286364

7

c-Ha-Ras mutants with point mutations in Gln-Val-Val region have reduced inhibitory activity toward cathepsin B.

Hiwasa T, Fujita-Yoshigaki J, Shirouzu M, Koide H, Sawada T, Sakiyama S, Yokoyama S. Hiwasa T, et al. Among authors: shirouzu m. Cancer Lett. 1993 May 14;69(3):161-5. doi: 10.1016/0304-3835(93)90169-a. Cancer Lett. 1993. PMID: 8513441

8

Cysteine-rich region of Raf-1 interacts with activator domain of post-translationally modified Ha-Ras.

Hu CD, Kariya K, Tamada M, Akasaka K, Shirouzu M, Yokoyama S, Kataoka T. Hu CD, et al. Among authors: shirouzu m. J Biol Chem. 1995 Dec 22;270(51):30274-7. doi: 10.1074/jbc.270.51.30274. J Biol Chem. 1995. PMID: 8530446 Free article.

9

Differential structural requirements for interaction of Ras protein with its distinct downstream effectors.

Akasaka K, Tamada M, Wang F, Kariya K, Shima F, Kikuchi A, Yamamoto M, Shirouzu M, Yokoyama S, Kataoka T. Akasaka K, et al. Among authors: shirouzu m. J Biol Chem. 1996 Mar 8;271(10):5353-60. doi: 10.1074/jbc.271.10.5353. J Biol Chem. 1996. PMID: 8621388 Free article.

10

Difference in the mechanism of interaction of Raf-1 and B-Raf with H-Ras.

Shinkai M, Masuda T, Kariya K, Tamada M, Shirouzu M, Yokoyama S, Kataoka T. Shinkai M, et al. Among authors: shirouzu m. Biochem Biophys Res Commun. 1996 Jun 25;223(3):729-34. doi: 10.1006/bbrc.1996.0964. Biochem Biophys Res Commun. 1996. PMID: 8687465

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