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Study Design and Protocol for a Randomized Controlled Trial to Assess Long-Term Efficacy and Safety of a Triple Combination of Ezetimibe, Fenofibrate, and Moderate-Intensity Statin in Patients with Type 2 Diabetes and Modifiable Cardiovascular Risk Factors (ENSEMBLE).
Kim NH, Lee J, Chon S, Yu JM, Jeong IK, Lim S, Kim WJ, Song K, Cho HC, Yu HM, Kim KA, Kim SS, Lee SH, Kim CH, Kwak SH, Lee YH, Chung CH, Lee S, Jin HY, Lee JH, Koh G, Kim SY, Kim J, Lee JH, Kim TN, Jeon HJ, Lee JH, Jeon JH, Yoo HJ, Kim HK, Park HK, Nam-Goong IS, Hong S, Ahn CW, Yu JH, Park JH, Park KG, Park CH, Joung KH, Ryu OH, Park KY, Hong EG, Cha BS, Won KC, Chung YS, Kim SG. Kim NH, et al. Endocrinol Metab (Seoul). 2024 Oct;39(5):722-731. doi: 10.3803/EnM.2024.1995. Epub 2024 Aug 22. Endocrinol Metab (Seoul). 2024. PMID: 39174014 Free PMC article.
Fibrates lower triglyceride levels and increase high-density lipoprotein cholesterol (HDL-C) levels via peroxisome proliferator- activated receptor alpha agonism. Therefore, when combined, these drugs effectively lower non-HDL-C levels. ...
Fibrates lower triglyceride levels and increase high-density lipoprotein cholesterol (HDL-C) levels via peroxisome proliferator- activated r …
Antidiabetic and anti-obesity properties of a polyphenol-rich flower extract from Tagetes erecta L. and its effects on Caenorhabditis elegans fat storages.
Núñez S, Moliner C, Valero MS, Mustafa AM, Maggi F, Gómez-Rincón C, López V. Núñez S, et al. J Physiol Biochem. 2023 May;79(2):427-440. doi: 10.1007/s13105-023-00953-5. Epub 2023 Mar 24. J Physiol Biochem. 2023. PMID: 36961724 Free PMC article.
The capacity to inhibit the enzymes lipase and alpha-glucosidase, as well as the inhibition of advance glycation end-products (AGEs) was tested in vitro. ...Extracts from both cultivars (yellow and orange) T. erecta presented in vitro inhibitory activity against the enzyme …
The capacity to inhibit the enzymes lipase and alpha-glucosidase, as well as the inhibition of advance glycation end-products (AGEs) …
Five-Year Retention of Perampanel and Polytherapy Patterns: 328 Patients From a Single Center in South Korea.
Park KI, Hwang S, Son H, Chu K, Jung KY, Lee SK. Park KI, et al. J Clin Neurol. 2023 Jul;19(4):358-364. doi: 10.3988/jcn.2022.0338. J Clin Neurol. 2023. PMID: 37417431 Free PMC article.
BACKGROUND AND PURPOSE: Perampanel (PER) is an alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid antagonist used to treat focal and generalized epilepsy. ...
BACKGROUND AND PURPOSE: Perampanel (PER) is an alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid antagonist used to treat foca …
Validation of the Korean Version of the Questionnaire for Impulsive-Compulsive Disorders in Parkinson's Disease Rating Scale.
Choi JH, Lee JY, Cho JW, Ko SB, Ahn TB, Kim SJ, Cheon SM, Kim JS, Kim YJ, Ma HI, Baik JS, Lee PH, Chung SJ, Kim JM, Song IU, Kim HJ, Sung YH, Kwon DY, Lee JH, Kim JY, Kim JS, Yun JY, Kim HJ, Hong JY, Kim MJ, Youn J, Kim JS, Oh ES, Yang HJ, Yoon WT, You S, Kwon KY, Park HE, Lee SY, Kim Y, Kim HT, Park MY. Choi JH, et al. J Clin Neurol. 2020 Apr;16(2):245-253. doi: 10.3988/jcn.2020.16.2.245. J Clin Neurol. 2020. PMID: 32319241 Free PMC article.
The internal consistency of the K-QUIP-RS was indicated by a Cronbach's alpha coefficient of 0.846, as was the test-retest reliability by a Guttman split-half coefficient of 0.808. ...
The internal consistency of the K-QUIP-RS was indicated by a Cronbach's alpha coefficient of 0.846, as was the test-retest reliabilit …
Investigation on improvement of enantioseparation based on clindamycin phosphate by chiral deep eutectic solvents in capillary electrophoresis.
Ma X, Fan Z, Tang Z, Cai L. Ma X, et al. J Sep Sci. 2024 Feb;47(3):e2300847. doi: 10.1002/jssc.202300847. J Sep Sci. 2024. PMID: 38356235
We synthesized a series of deep eutectic solvents with choline chloride as hydrogen bond acceptor and three alpha-hydroxyl acids (l-lactic acid, l-malic acid, and l-tartaric acid) as hydrogen bond donors. ...
We synthesized a series of deep eutectic solvents with choline chloride as hydrogen bond acceptor and three alpha-hydroxyl acids (l-l …
Efficacy and safety of Shu-gan-qing-re formula for generalized anxiety disorder: study protocol for a multi-center, prospective, double-blind, double-dummy, randomized controlled trial.
Chen P, Zhu H, Ning Y, Yin D, Jia H. Chen P, et al. Trials. 2020 Mar 14;21(1):266. doi: 10.1186/s13063-020-4186-6. Trials. 2020. PMID: 32171323 Free PMC article.
Outcome measurements include Hamilton Anxiety Rating Scale (HAM-A), Hamilton Depression Rating Scale-17 (HAMD-17), Clinical Global Impression-Improvement Scale (CGI-I), Traditional Chinese Medicine Syndrome Scale for GAD, and pro-inflammatory cytokine tests: interleukin-1 beta (I …
Outcome measurements include Hamilton Anxiety Rating Scale (HAM-A), Hamilton Depression Rating Scale-17 (HAMD-17), Clinical Global Impressio …
The Clinical Utility of Serum Alpha-1-Acid Glycoprotein in Reflecting the Cross-Sectional Activity of Antineutrophil Cytoplasmic Antibody-Associated Vasculitis: A Single-Centre Retrospective Study.
Yoo J, Yoon T, Park YB, Ahn SS, Lee SW. Yoo J, et al. Medicina (Kaunas). 2024 Jul 26;60(8):1212. doi: 10.3390/medicina60081212. Medicina (Kaunas). 2024. PMID: 39202493 Free PMC article.
Background and Objectives: This study investigated whether serum alpha-1-acid glycoprotein (AGP) at diagnosis could reflect the cross-sectional activity represented by the Birmingham vasculitis activity score (BVAS) and further predict poor outcomes during follow-up in pat …
Background and Objectives: This study investigated whether serum alpha-1-acid glycoprotein (AGP) at diagnosis could reflect the cross …
Ultrasound-assisted extraction versus traditional Soxhlet apparatus for the obtention of polyphenols, carotenoids and tocopherols from Tagetes erecta L. flowers.
Núñez S, Valero MS, Mustafa AM, Caprioli G, Maggi F, Gómez-Rincón C, López V. Núñez S, et al. J Sci Food Agric. 2024 Dec 23. doi: 10.1002/jsfa.14105. Online ahead of print. J Sci Food Agric. 2024. PMID: 39716808
The highest content of tocopherols was obtained in the yellow cultivar extracted by Soxhlet (6499.3 21.2 and 4671.0 92.9 mg kg(-1) dry extract for alpha- and gamma-tocopherol). The antioxidant potential resulted higher in the orange Soxhlet extract, whereas the yellow Soxh …
The highest content of tocopherols was obtained in the yellow cultivar extracted by Soxhlet (6499.3 21.2 and 4671.0 92.9 mg kg(-1) dry extra …