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Blood biomarkers on admission in acute traumatic brain injury: Relations to severity, CT findings and care path in the CENTER-TBI study.
Czeiter E, Amrein K, Gravesteijn BY, Lecky F, Menon DK, Mondello S, Newcombe VFJ, Richter S, Steyerberg EW, Vyvere TV, Verheyden J, Xu H, Yang Z, Maas AIR, Wang KKW, Büki A; CENTER-TBI Participants and Investigators. Czeiter E, et al. EBioMedicine. 2020 Jun;56:102785. doi: 10.1016/j.ebiom.2020.102785. Epub 2020 May 25. EBioMedicine. 2020. PMID: 32464528 Free PMC article. Clinical Trial.
METHODS: We analyzed six serum biomarkers (S100B, NSE, GFAP, UCH-L1, NFL and t-tau) obtained <24 h post-injury from 2867 patients with any severity of TBI in the Collaborative European NeuroTrauma Effectiveness Research (CENTER-TBI) Core Study, a prospective, mul …
METHODS: We analyzed six serum biomarkers (S100B, NSE, GFAP, UCH-L1, NFL and t-tau) obtained <24 h post-injury from 2867 patients with an …
Case-mix, care pathways, and outcomes in patients with traumatic brain injury in CENTER-TBI: a European prospective, multicentre, longitudinal, cohort study.
Steyerberg EW, Wiegers E, Sewalt C, Buki A, Citerio G, De Keyser V, Ercole A, Kunzmann K, Lanyon L, Lecky F, Lingsma H, Manley G, Nelson D, Peul W, Stocchetti N, von Steinbüchel N, Vande Vyvere T, Verheyden J, Wilson L, Maas AIR, Menon DK; CENTER-TBI Participants and Investigators. Steyerberg EW, et al. Lancet Neurol. 2019 Oct;18(10):923-934. doi: 10.1016/S1474-4422(19)30232-7. Lancet Neurol. 2019. PMID: 31526754 Free article.
We aimed to characterise patient case-mix, care pathways, and outcomes of TBI. METHODS: CENTER-TBI is a Europe-based, observational cohort study, consisting of a core study and a registry. ...
We aimed to characterise patient case-mix, care pathways, and outcomes of TBI. METHODS: CENTER-TBI is a Europe-based, observat …
Rehabilitation and outcomes after complicated vs uncomplicated mild TBI: results from the CENTER-TBI study.
Howe EI, Zeldovich M, Andelic N, von Steinbuechel N, Fure SCR, Borgen IMH, Forslund MV, Hellstrøm T, Søberg HL, Sveen U, Rasmussen M, Kleffelgaard I, Tverdal C, Helseth E, Løvstad M, Lu J, Arango-Lasprilla JC, Tenovuo O, Azouvi P, Dawes H, Roe C; CENTER-TBI participants and investigators. Howe EI, et al. BMC Health Serv Res. 2022 Dec 16;22(1):1536. doi: 10.1186/s12913-022-08908-0. BMC Health Serv Res. 2022. PMID: 36527074 Free PMC article. Clinical Trial.
METHODS: Patients (n = 1379) with mTBI from the Collaborative European NeuroTrauma Effectiveness Research in TBI (CENTER-TBI) study who reported whether they received rehabilitation services during the first six months post-injury and who participated in outcome ass …
METHODS: Patients (n = 1379) with mTBI from the Collaborative European NeuroTrauma Effectiveness Research in TBI (CENTER-TBI) …
Clinical descriptors of disease trajectories in patients with traumatic brain injury in the intensive care unit (CENTER-TBI): a multicentre observational cohort study.
Åkerlund CAI, Holst A, Bhattacharyay S, Stocchetti N, Steyerberg E, Smielewski P, Menon DK, Ercole A, Nelson DW; CENTER-TBI participants and investigators. Åkerlund CAI, et al. Lancet Neurol. 2024 Jan;23(1):71-80. doi: 10.1016/S1474-4422(23)00358-7. Epub 2023 Nov 14. Lancet Neurol. 2024. PMID: 37977157
METHODS: We used data from the Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) prospective observational cohort study. We included patients aged 18 years or older with traumatic brain injury who were admitted to the I …
METHODS: We used data from the Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI …
Early systemic insults following traumatic brain injury: association with biomarker profiles, therapy for intracranial hypertension, and neurological outcomes-an analysis of CENTER-TBI data.
Robba C, Graziano F, Picetti E, Åkerlund C, Addis A, Pastore G, Sivero M, Rebora P, Galimberti S, Stocchetti N, Maas A, Menon DK, Citerio G; CENTER-TBI Participants and Investigators. Robba C, et al. Intensive Care Med. 2024 Mar;50(3):371-384. doi: 10.1007/s00134-024-07324-8. Epub 2024 Feb 20. Intensive Care Med. 2024. PMID: 38376517 Free PMC article.
METHODS: From patients recruited to the Collaborative European neurotrauma effectiveness research in TBI (CENTER-TBI) study, we documented the prevalence and risk factors for SIs and analysed their effect on the levels of brain injury biomarkers [S100 calcium-bindin …
METHODS: From patients recruited to the Collaborative European neurotrauma effectiveness research in TBI (CENTER-TBI) study, w …
Serum metabolome associated with severity of acute traumatic brain injury.
Thomas I, Dickens AM, Posti JP, Czeiter E, Duberg D, Sinioja T, Kråkström M, Retel Helmrich IRA, Wang KKW, Maas AIR, Steyerberg EW, Menon DK, Tenovuo O, Hyötyläinen T, Büki A, Orešič M; CENTER-TBI Participants and Investigators. Thomas I, et al. Nat Commun. 2022 May 10;13(1):2545. doi: 10.1038/s41467-022-30227-5. Nat Commun. 2022. PMID: 35538079 Free PMC article.
We performed a comprehensive metabolomics study in a cohort of 716 patients with TBI and non-TBI reference patients (orthopedic, internal medicine, and other neurological patients) from the Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CE …
We performed a comprehensive metabolomics study in a cohort of 716 patients with TBI and non-TBI reference patients (orthopedic, internal me …
Frequency and predictors of headache in the first 12 months after traumatic brain injury: results from CENTER-TBI.
Howe EI, Andelic N, Brunborg C, Zeldovich M, Helseth E, Skandsen T, Olsen A, Fure SCR, Theadom A, Rauen K, Madsen BÅ, Jacobs B, van der Naalt J, Tartaglia MC, Einarsen CE, Storvig G, Tronvik E, Tverdal C, von Steinbüchel N, Røe C, Hellstrøm T; CENTER-TBI Participants and Investigators. Howe EI, et al. J Headache Pain. 2024 Mar 25;25(1):44. doi: 10.1186/s10194-024-01751-0. J Headache Pain. 2024. PMID: 38528477 Free PMC article.
METHODS: A large patient sample from the Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) prospective observational cohort study was used. Patients were stratified based on their clinical care pathway: admitted to an e …
METHODS: A large patient sample from the Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER- …
Contrasting Characteristics and Outcomes of Sports-Related and Non-Sports-Related Traumatic Brain Injury.
Ntikas M, Stewart W, Ietswaart M, Hunter AM, Maas AIR, Menon DK, Wilson L; CENTER-TBI participants and investigators. Ntikas M, et al. JAMA Netw Open. 2024 Jan 2;7(1):e2353318. doi: 10.1001/jamanetworkopen.2023.53318. JAMA Netw Open. 2024. PMID: 38265796 Free PMC article.
DESIGN, SETTING, AND PARTICIPANTS: The CENTER-TBI (Collaborative European NeuroTrauma Effectiveness Research in TBI) observational cohort study was conducted at hospitals in 18 countries. ...
DESIGN, SETTING, AND PARTICIPANTS: The CENTER-TBI (Collaborative European NeuroTrauma Effectiveness Research in TBI) observati …
Early versus delayed cranioplasty after decompressive craniectomy in traumatic brain injury: a multicenter observational study within CENTER-TBI and Net-QuRe.
Vreeburg RJG, Singh RD, van Erp IAM, Korhonen TK, Yue JK, Mee H, Timofeev I, Kolias A, Helmy A, Depreitere B, Moojen WA, Younsi A, Hutchinson P, Manley GT, Steyerberg EW, de Ruiter GCW, Maas AIR, Peul WC, van Dijck JTJM, den Boogert HF, Posti JP, van Essen TA; for the CENTER-TBI Participants and Investigators. Vreeburg RJG, et al. J Neurosurg. 2024 Apr 26;141(4):895-907. doi: 10.3171/2024.1.JNS232172. Print 2024 Oct 1. J Neurosurg. 2024. PMID: 38669706
METHODS: The authors analyzed participants enrolled in the Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) and the Neurotraumatology Quality Registry (Net-QuRe) studies who were diagnosed with TBI and underwent DC and …
METHODS: The authors analyzed participants enrolled in the Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Inju …
Health care utilization and outcomes in older adults after Traumatic Brain Injury: A CENTER-TBI study.
van der Vlegel M, Mikolić A, Lee Hee Q, Kaplan ZLR, Retel Helmrich IRA, van Veen E, Andelic N, Steinbuechel NV, Plass AM, Zeldovich M, Wilson L, Maas AIR, Haagsma JA, Polinder S; CENTER-TBI Participants and Investigators. van der Vlegel M, et al. Injury. 2022 Aug;53(8):2774-2782. doi: 10.1016/j.injury.2022.05.009. Epub 2022 May 26. Injury. 2022. PMID: 35725508 Free article.
METHODS: We used data from the prospective multi-center Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) study. In-hospital and post-hospital health care utilization and outcomes were described for patients aged 65 yea …
METHODS: We used data from the prospective multi-center Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury …
38 results