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2007 1
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12 results

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Page 1
Fasting mimicking diet as an adjunct to neoadjuvant chemotherapy for breast cancer in the multicentre randomized phase 2 DIRECT trial.
de Groot S, Lugtenberg RT, Cohen D, Welters MJP, Ehsan I, Vreeswijk MPG, Smit VTHBM, de Graaf H, Heijns JB, Portielje JEA, van de Wouw AJ, Imholz ALT, Kessels LW, Vrijaldenhoven S, Baars A, Kranenbarg EM, Carpentier MD, Putter H, van der Hoeven JJM, Nortier JWR, Longo VD, Pijl H, Kroep JR; Dutch Breast Cancer Research Group (BOOG). de Groot S, et al. Nat Commun. 2020 Jun 23;11(1):3083. doi: 10.1038/s41467-020-16138-3. Nat Commun. 2020. PMID: 32576828 Free PMC article. Clinical Trial.
Short-term fasting protects tumor-bearing mice against the toxic effects of chemotherapy while enhancing therapeutic efficacy. We randomized 131 patients with HER2-negative stage II/III breast cancer, without diabetes and a BMI over 18 kg m(-2), to receive either a fasting …
Short-term fasting protects tumor-bearing mice against the toxic effects of chemotherapy while enhancing therapeutic efficacy. We ran …
Core planar cell polarity genes VANGL1 and VANGL2 in predisposition to congenital vertebral malformations.
Feng X, Ye Y, Zhang J, Zhang Y, Zhao S, Mak JCW, Otomo N, Zhao Z, Niu Y, Yonezawa Y, Li G, Lin M, Li X, Cheung PWH, Xu K, Takeda K, Wang S, Xie J, Kotani T, Choi VNT, Song YQ, Yang Y, Luk KDK, Lee KS, Li Z, Li PS, Leung CYH, Lin X, Wang X, Qiu G; DISCO (Deciphering disorders Involving Scoliosis and COmorbidities) study group; Watanabe K; Japanese Early Onset Scoliosis Research Group; Wu Z, Posey JE, Ikegawa S, Lupski JR, Cheung JPY, Zhang TJ, Gao B, Wu N. Feng X, et al. Proc Natl Acad Sci U S A. 2024 Apr 30;121(18):e2310283121. doi: 10.1073/pnas.2310283121. Epub 2024 Apr 26. Proc Natl Acad Sci U S A. 2024. PMID: 38669183 Free PMC article.
Furthermore, we found that Vangl1 knock-in (p.R258H) mice exhibited vertebral malformations in a Vangl gene dose- and environment-dependent manner. ...
Furthermore, we found that Vangl1 knock-in (p.R258H) mice exhibited vertebral malformations in a Vangl gene dose- and environment-dep …
Contactin 5 and Apolipoproteins Interplay in Alzheimer's Disease.
Dauar MT, Picard C, Labonté A, Breitner J, Rosa-Neto P, Villeneuve S, Poirier J; PREVENT-AD Research Group. Dauar MT, et al. J Alzheimers Dis. 2024;98(4):1361-1375. doi: 10.3233/JAD-231003. J Alzheimers Dis. 2024. PMID: 38578887
Gene expression was measured using polymerase chain reaction in the frontal cortex of autopsied-confirmed AD (n = 57) and control subjects (n = 31) and in the hippocampi of mice following entorhinal cortex lesions. RESULTS: Contactin 5 positively correlated with apolipopro …
Gene expression was measured using polymerase chain reaction in the frontal cortex of autopsied-confirmed AD (n = 57) and control subjects ( …
Comparative proteomics of inhaled silver nanoparticles in healthy and allergen provoked mice.
Su CL, Chen TT, Chang CC, Chuang KJ, Wu CK, Liu WT, Ho KF, Lee KY, Ho SC, Tseng HE, Chuang HC, Cheng TJ; Taiwan CardioPulmonary Research Group (T-CPR). Su CL, et al. Int J Nanomedicine. 2013;8:2783-99. doi: 10.2147/IJN.S46997. Epub 2013 Aug 2. Int J Nanomedicine. 2013. PMID: 23946650 Free PMC article.
RESULTS: In total, 106 and 79 AgNP-unique proteins were identified in the BALF of control and allergic mice, respectively. Additionally, 40 and 26 AgNP-unique proteins were found in the plasma of control and allergic mice, respectively. ...In addition, we observed 1 …
RESULTS: In total, 106 and 79 AgNP-unique proteins were identified in the BALF of control and allergic mice, respectively. Additional …
Allergenicity and toxicology of inhaled silver nanoparticles in allergen-provocation mice models.
Chuang HC, Hsiao TC, Wu CK, Chang HH, Lee CH, Chang CC, Cheng TJ; Taiwan CardioPulmonary Research Group (T-CPR). Chuang HC, et al. Int J Nanomedicine. 2013;8:4495-506. doi: 10.2147/IJN.S52239. Epub 2013 Nov 22. Int J Nanomedicine. 2013. PMID: 24285922 Free PMC article.
AgNP evoked neutrophil, lymphocyte and eosinophil infiltration into the airways and elevated the levels of allergic markers (immunoglobulin E [IgE] and leukotriene E4 [LTE4]), the type 2 T helper (Th2) cytokine interleukin-13 (IL-13), and oxidative stress (8-hydroxy-2'-deoxyguano …
AgNP evoked neutrophil, lymphocyte and eosinophil infiltration into the airways and elevated the levels of allergic markers (immunoglobulin …
Reaming of femoral fractures with different reaming irrigator aspirator systems shows distinct effects on cardiac function after experimental polytrauma.
Lackner I, Weber B, Miclau T, Holzwarth N, Baur M, Gebhard F, Teuben M, Halvachizadeh S, Cinelli P, Pfeifer R, Lipiski M, Cesarovic N, Haffner-Luntzer M, Pape HC, Kalbitz M; TREAT Research Group. Lackner I, et al. J Orthop Res. 2020 Dec;38(12):2608-2618. doi: 10.1002/jor.24830. Epub 2020 Sep 1. J Orthop Res. 2020. PMID: 32827323 Free article.
Angiogenic properties of human placenta-derived adherent cells and efficacy in hindlimb ischemia.
Francki A, Labazzo K, He S, Baum EZ, Abbot SE, Herzberg U, Hofgartner W, Hariri R; Celgene Cellular Therapeutics Research Group. Francki A, et al. J Vasc Surg. 2016 Sep;64(3):746-756.e1. doi: 10.1016/j.jvs.2015.04.387. Epub 2015 Jun 6. J Vasc Surg. 2016. PMID: 26054585 Free article.
Angiogenic effects were assessed in the chick chorioallantoic membrane assay. Hindlimb ischemia (HLI) was induced in mice and rats by femoral artery transection, and blood flow and blood vessel density were monitored in vivo by laser Doppler and angiography in the ischemic …
Angiogenic effects were assessed in the chick chorioallantoic membrane assay. Hindlimb ischemia (HLI) was induced in mice and rats by …
Bone Density Loss Is Associated With Blood Cell Counts.
Valderrábano RJ, Lui LY, Lee J, Cummings SR, Orwoll ES, Hoffman AR, Wu JY; Osteoporotic Fractures in Men (MrOS) Study Research Group. Valderrábano RJ, et al. J Bone Miner Res. 2017 Feb;32(2):212-220. doi: 10.1002/jbmr.3000. Epub 2016 Nov 2. J Bone Miner Res. 2017. PMID: 27653240 Free PMC article.
Hematopoiesis depends on a supportive microenvironment. Preclinical studies in mice have demonstrated that osteoblasts influence the development of blood cells, particularly erythrocytes, B lymphocytes, and neutrophils. ...
Hematopoiesis depends on a supportive microenvironment. Preclinical studies in mice have demonstrated that osteoblasts influence the …
TBX6-associated congenital scoliosis (TACS) as a clinically distinguishable subtype of congenital scoliosis: further evidence supporting the compound inheritance and TBX6 gene dosage model.
Liu J, Wu N; Deciphering Disorders Involving Scoliosis and COmorbidities (DISCO) study; Yang N, Takeda K, Chen W, Li W, Du R, Liu S, Zhou Y, Zhang L, Liu Z, Zuo Y, Zhao S, Blank R, Pehlivan D, Dong S, Zhang J, Shen J, Si N, Wang Y, Liu G, Li S, Zhao Y, Zhao H, Chen Y, Zhao Y, Song X, Hu J, Lin M, Tian Y, Yuan B, Yu K, Niu Y, Yu B, Li X, Chen J, Yan Z, Zhu Q, Meng X, Chen X, Su J, Zhao X, Wang X, Ming Y, Li X, Raggio CL, Zhang B, Weng X, Zhang S, Zhang X, Watanabe K, Matsumoto M; Japan Early Onset Scoliosis Research Group; Jin L, Shen Y, Sobreira NL, Posey JE, Giampietro PF, Valle D; Baylor-Hopkins Center for Mendelian Genomics; Liu P, Wu Z, Ikegawa S, Lupski JR, Zhang F, Qiu G. Liu J, et al. Genet Med. 2019 Jul;21(7):1548-1558. doi: 10.1038/s41436-018-0377-x. Epub 2019 Jan 14. Genet Med. 2019. PMID: 30636772 Free PMC article.
Increased endocannabinoid levels reduce the development of precancerous lesions in the mouse colon.
Izzo AA, Aviello G, Petrosino S, Orlando P, Marsicano G, Lutz B, Borrelli F, Capasso R, Nigam S, Capasso F, Di Marzo V; Endocannabinoid Research Group. Izzo AA, et al. J Mol Med (Berl). 2008 Jan;86(1):89-98. doi: 10.1007/s00109-007-0248-4. Epub 2007 Sep 6. J Mol Med (Berl). 2008. PMID: 17823781 Free PMC article.
No differences in ACF formation were observed between CB(1) receptor-deficient and wild-type mice. It is concluded that pharmacological enhancement of endocannabinoid levels (through inhibition of endocannabinoid hydrolysis) reduces the development of precancerous lesions …
No differences in ACF formation were observed between CB(1) receptor-deficient and wild-type mice. It is concluded that pharmacologic …
12 results