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Klebsiella oxytoca inhibits Salmonella infection through multiple microbiota-context-dependent mechanisms.
Osbelt L, Almási ÉDH, Wende M, Kienesberger S, Voltz A, Lesker TR, Muthukumarasamy U, Knischewski N, Nordmann E, Bielecka AA, Giralt-Zúñiga M, Kaganovitch E, Kühne C, Baier C, Pietsch M, Müsken M, Greweling-Pils MC, Breinbauer R, Flieger A, Schlüter D, Müller R, Erhardt M, Zechner EL, Strowig T. Osbelt L, et al. Nat Microbiol. 2024 Jul;9(7):1792-1811. doi: 10.1038/s41564-024-01710-0. Epub 2024 Jun 11. Nat Microbiol. 2024. PMID: 38862602 Free PMC article.
Systematic interrogation of CRISPR antimicrobials in Klebsiella pneumoniae reveals nuclease-, guide- and strain-dependent features influencing antimicrobial activity.
Vialetto E, Miele S, Goren MG, Yu J, Yu Y, Collias D, Beamud B, Osbelt L, Lourenço M, Strowig T, Brisse S, Barquist L, Qimron U, Bikard D, Beisel CL. Vialetto E, et al. Nucleic Acids Res. 2024 Jun 10;52(10):6079-6091. doi: 10.1093/nar/gkae281. Nucleic Acids Res. 2024. PMID: 38661215 Free PMC article.
Klebsiella oxytoca facilitates microbiome recovery via antibiotic degradation and restores colonization resistance in a diet-dependent manner.
Almási ÉDH, Eisenhard L, Osbelt L, Lesker TR, Vetter AC, Knischewski N, Bielecka AA, Gronow A, Muthukumarasamy U, Wende M, Tawk C, Neumann-Schaal M, Brönstrup M, Strowig T. Almási ÉDH, et al. Nat Commun. 2025 Jan 9;16(1):551. doi: 10.1038/s41467-024-55800-y. Nat Commun. 2025. PMID: 39789003 Free PMC article.