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Tumor hypoxia induces nuclear paraspeckle formation through HIF-2α dependent transcriptional activation of NEAT1 leading to cancer cell survival.
Oncogene. 2015 Aug 20;34(34):4482-90. doi: 10.1038/onc.2014.378. Epub 2014 Nov 24.
Oncogene. 2015.
PMID: 25417700
Free PMC article.
Common genetic variants at the 11q13.3 renal cancer susceptibility locus influence binding of HIF to an enhancer of cyclin D1 expression.
Schödel J, Bardella C, Sciesielski LK, Brown JM, Pugh CW, Buckle V, Tomlinson IP, Ratcliffe PJ, Mole DR.
Schödel J, et al.
Nat Genet. 2012 Mar 11;44(4):420-5, S1-2. doi: 10.1038/ng.2204.
Nat Genet. 2012.
PMID: 22406644
Free PMC article.
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