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Afferent and efferent cellular interactions in natural resistance directed against MHC class I deficient tumor grafts.
Ljunggren HG, Ohlén C, Höglund P, Yamasaki T, Klein G, Kärre K. Ljunggren HG, et al. J Immunol. 1988 Jan 15;140(2):671-8. J Immunol. 1988. PMID: 3335786
Such mixing experiments revealed a more efficient cold target inhibition by the H-2-deficient cells, although no difference was seen between these and the H-2-positive wild-type cells in target binding assays. When Thy-1.2+, nylon wool adherent or phagocytic populations we …
Such mixing experiments revealed a more efficient cold target inhibition by the H-2-deficient cells, although no difference was seen between …
Transfection of beta 2-microglobulin restores IFN-mediated protection from natural killer cell lysis in YAC-1 lymphoma variants.
Ljunggren HG, Sturmhöfel K, Wolpert E, Hämmerling GJ, Kärre K. Ljunggren HG, et al. J Immunol. 1990 Jul 1;145(1):380-6. J Immunol. 1990. PMID: 2113557
IFN-gamma treatment of the NK-sensitive murine YAC-1 lymphoma results in reduced sensitivity to NK cell-mediated lysis in parallel with increased expression of its constitutively low MHC class I expression. ...Here beta 2m transfection restored the YAC-1 phenotype w …
IFN-gamma treatment of the NK-sensitive murine YAC-1 lymphoma results in reduced sensitivity to NK cell-mediated lysis in parallel wi …
Enhanced H-2 expression and T-cell-dependent rejection after intracerebral transplantation of the murine lymphoma YAC-1.
Yamasaki T, Ljunggren HG, Ohlén C, Klein G, Kärre K. Yamasaki T, et al. Cell Immunol. 1989 May;120(2):387-95. doi: 10.1016/0008-8749(89)90206-2. Cell Immunol. 1989. PMID: 2785859
The relationship between MHC class I (H-2) expression and tumorigenicity was investigated after intracerebral inoculation of the murine lymphoma YAC-1 and its H-2 negative variant, A.H-2-. YAC-1 was less tumorigenic than A.H-2- in normal as well as NK-depleted synge …
The relationship between MHC class I (H-2) expression and tumorigenicity was investigated after intracerebral inoculation of the murine lymp …
Molecular analysis of H-2-deficient lymphoma lines. Distinct defects in biosynthesis and association of MHC class I heavy chains and beta 2-microglobulin observed in cells with increased sensitivity to NK cell lysis.
Ljunggren HG, Pääbo S, Cochet M, Kling G, Kourilsky P, Kärre K. Ljunggren HG, et al. J Immunol. 1989 Apr 15;142(8):2911-7. J Immunol. 1989. PMID: 2467945
It has previously been reported that MHC class I-deficient RBL-5 and YAC-1 lymphoma sublines show an enhanced NK sensitivity in vitro. In the present study such lymphoma variants were found to have different defects in H-2 biosynthesis such as 1) reduced beta 2-micr …
It has previously been reported that MHC class I-deficient RBL-5 and YAC-1 lymphoma sublines show an enhanced NK sensitivity in vitro …