REEP2 enhances sweet receptor function by recruitment to lipid rafts.
Ilegems E, Iwatsuki K, Kokrashvili Z, Benard O, Ninomiya Y, Margolskee RF.
Ilegems E, et al.
J Neurosci. 2010 Oct 13;30(41):13774-83. doi: 10.1523/JNEUROSCI.0091-10.2010.
J Neurosci. 2010.
PMID: 20943918
Free PMC article.
We determined that REEP2 is an integral membrane protein expressed in taste cells, physically associates with both subunits of the type 1 taste receptor 2 and type 1 taste receptor 3 sweet receptor and specifically enhances responses to tastants of heterologously ex …
We determined that REEP2 is an integral membrane protein expressed in taste cells, physically associates with both subunits of the type 1 …