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Conduction slowing and sudden arrhythmic death in mice with cardiac-restricted inactivation of connexin43.
Gutstein DE, Morley GE, Tamaddon H, Vaidya D, Schneider MD, Chen J, Chien KR, Stuhlmann H, Fishman GI. Gutstein DE, et al. Circ Res. 2001 Feb 16;88(3):333-9. doi: 10.1161/01.res.88.3.333. Circ Res. 2001. PMID: 11179202 Free PMC article.
Optical mapping of the epicardial electrical activation pattern in Cx43 conditional knockout mice revealed that ventricular conduction velocity was significantly slowed by up to 55% in the transverse direction and 42% in the longitudinal direction, resulting in an increase in ani …
Optical mapping of the epicardial electrical activation pattern in Cx43 conditional knockout mice revealed that ventricular conduction veloc …
The organization of adherens junctions and desmosomes at the cardiac intercalated disc is independent of gap junctions.
Gutstein DE, Liu FY, Meyers MB, Choo A, Fishman GI. Gutstein DE, et al. J Cell Sci. 2003 Mar 1;116(Pt 5):875-85. doi: 10.1242/jcs.00258. J Cell Sci. 2003. PMID: 12571285
We found that the cardiac adherens junctions, desmosomes and their associated catenins, as well as vinculin and ZO-1, maintain their normal abundance, structural appearance and localization in the absence of Cx43. ...
We found that the cardiac adherens junctions, desmosomes and their associated catenins, as well as vinculin and ZO-1, maintain their …