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Distinct functional and molecular profiles between physiological and pathological atrial enlargement offer potential new therapeutic opportunities for atrial fibrillation.
Chen YC, Wijekoon S, Matsumoto A, Luo J, Kiriazis H, Masterman E, Yildiz G, Cross J, Parslow AC, Chooi R, Sadoshima J, Greening DW, Weeks KL, McMullen JR. Chen YC, et al. Clin Sci (Lond). 2024 Aug 7;138(15):941-962. doi: 10.1042/CS20240178. Clin Sci (Lond). 2024. PMID: 39018488 Free PMC article.
Estrogen receptor alpha deficiency in cardiomyocytes reprograms the heart-derived extracellular vesicle proteome and induces obesity in female mice.
Tham YK, Bernardo BC, Claridge B, Yildiz GS, Woon LM, Bond S, Fang H, Ooi JYY, Matsumoto A, Luo J, Tai CMK, Harmawan CA, Kiriazis H, Donner DG, Mellett NA, Abel ED, Khan SA, De Souza DP, Doomun SNE, Liu K, Xiang R, Singh M, Inouye M, Meikle PJ, Weeks KL, Drew BG, Greening DW, McMullen JR. Tham YK, et al. Nat Cardiovasc Res. 2023 Mar;2(3):268-289. doi: 10.1038/s44161-023-00223-z. Epub 2023 Mar 9. Nat Cardiovasc Res. 2023. PMID: 39196021