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Ppp6c deficiency accelerates K-rasG12D -induced tongue carcinogenesis.
Kishimoto K, Kanazawa K, Nomura M, Tanaka T, Shigemoto-Kuroda T, Fukui K, Miura K, Kurosawa K, Kawai M, Kato H, Terasaki K, Sakamoto Y, Yamashita Y, Sato I, Tanuma N, Tamai K, Kitabayashi I, Matsuura K, Watanabe T, Yasuda J, Tsuji H, Shima H. Kishimoto K, et al. Cancer Med. 2021 Jul;10(13):4451-4464. doi: 10.1002/cam4.3962. Epub 2021 Jun 18. Cancer Med. 2021. PMID: 34145991 Free PMC article.
PP6 deficiency in mice with KRAS mutation and Trp53 loss promotes early death by PDAC with cachexia-like features.
Fukui K, Nomura M, Kishimoto K, Tanuma N, Kurosawa K, Kanazawa K, Kato H, Sato T, Miura S, Miura K, Sato I, Tsuji H, Yamashita Y, Tamai K, Watanabe T, Yasuda J, Tanaka T, Satoh K, Furukawa T, Jingu K, Shima H. Fukui K, et al. Cancer Sci. 2022 May;113(5):1613-1624. doi: 10.1111/cas.15315. Epub 2022 Mar 22. Cancer Sci. 2022. PMID: 35247012 Free PMC article.